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Aggresome Formation and Neurodegenerative Diseases : Therapeutic Implications

Author
OLZMANN, J. A1 ; LI, L1 ; CHIN, L. S1
[1] Department of Pharmacology, Emory University School of Medicine, Atlanta, GA 30322, United States
Source

Current medicinal chemistry. 2008, Vol 15, Num 1, pp 47-60, 14 p ; ref : 184 ref

ISSN
0929-8673
Scientific domain
Biochemistry, molecular biology, biophysics; Pharmacology drugs
Publisher
Bentham Science, Schiphol
Publication country
Netherlands
Document type
Article
Language
English
Author keyword
HDAC6 Neurodegenerative diseases aggresome ataxin-3 inclusion body parkin protein misfolding ubiquilin-1
Keyword (fr)
Autophagie Changement conformation Chaperon Corps inclusion Cytoprotecteur Maladie dégénérative Molécule petite Multicatalytic endopeptidase complex Parkine Pathologie du système nerveux Protéine choc thermique Protéine Relation structure activité Ubiquitin-protein ligase Agrésome Histone deacetylase Carbon-nitrogen ligases Enzyme Hydrolases Ligases Peptidases
Keyword (en)
Autophagy Conformational changes Chaperone Inclusion body Cytoprotector Degenerative disease Small molecule Multicatalytic endopeptidase complex Parkin Nervous system diseases Heat shock protein Protein Structure activity relation Ubiquitin-protein ligase Aggresome Carbon-nitrogen ligases Enzyme Hydrolases Ligases Peptidases
Keyword (es)
Autofagia Chaperone Cuerpo inclusión Citoprotector Enfermedad degenerativa Molécula pequeña Multicatalytic endopeptidase complex Parkin Sistema nervioso patología Proteína choque térmico Proteína Relación estructura actividad Ubiquitin-protein ligase Carbon-nitrogen ligases Enzima Hydrolases Ligases Peptidases
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02B Neuropharmacology / 002B02B11 Miscellaneous

Discipline
Pharmacological treatments
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
20262900

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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