Spisulosine (ES-285) induces prostate tumor PC-3 and LNCaP cell death by de novo synthesis of ceramide and PKCζ activation
- Author
- SANCHEZ, Ana M1 ; MALAGARIE-CAZENAVE, Sophie1 ; OLEA, Nuria1 ; VARA, Diana1 ; CUEVAS, Carmen2 ; DIAZ-LAVIADA, Inés1
[1] Department of Biochemistry and Molecular Biology, School of Medicine, University of Alcalá, 28871 Alcald de Henares, Madrid, Spain
[2] PhurmaMar, 28770 Colmenar Viejo, Madrid, Spain - Source
European journal of pharmacology. 2008, Vol 584, Num 2-3, pp 237-245, 9 p ; ref : 3/4 p
- CODEN
- EJPHAZ
- ISSN
- 0014-2999
- Scientific domain
- Pharmacology drugs
- Publisher
- Elsevier, Amsterdam
- Publication country
- Netherlands
- Document type
- Article
- Language
- English
- Author keyword
- Cancer Ceramide PKCζ Prostate Spisulosine
- Keyword (fr)
- Céramide Mort cellulaire Prostate Protein kinase C Tumeur de la prostate Tumeur maligne Spisulosine Appareil urogénital Cancer Enzyme Pathologie de l'appareil génital mâle Pathologie de l'appareil urinaire Pathologie de la prostate Sphingolipide Transferases
- Keyword (en)
- Ceramide Cell death Prostate Protein kinase C Prostate tumor Malignant tumor Urogenital system Cancer Enzyme Male genital diseases Urinary system disease Prostate disease Sphingolipid Transferases
- Keyword (es)
- Cerámida Muerte celular Prostata Protein kinase C Tumor prostata Tumor maligno Aparato urogenital Cáncer Enzima Aparato genital macho patología Aparato urinario patología Prostata patología Esfingolípido Transferases
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B14 Nephrology. Urinary tract diseases / 002B14D Tumors of the urinary system / 002B14D02 Urinary tract. Prostate gland
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B20 Gynecology. Andrology. Obstetrics / 002B20B Male genital diseases / 002B20B02 Tumors
- Discipline
- General pharmacology Gynecology. Andrology. Obstetrics Nephrology. Urinary tract diseases
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 20263421
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.ejphar.2008.02.011 
https://dx.doi.org/10.1016/j.ejphar.2008.02.011
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