Prospective, multicenter randomized GITMO/IIL trial comparing intensive (R-HDS) versus conventional (CHOP-R) chemoimmunotherapy in high-risk follicular lymphoma at diagnosis : the superior disease control of R-HDS does not translate into an overall survival advantage
- Author
- LADETTO, Marco1 ; DE MARCO, Federica1 ; GALLAMINI, Andrea10 ; POGLIANI, Enrico11 ; ROTA SCALABRINI, Delia12 ; CALLEA, Vincenzo13 ; DI RAIMONDO, Francesco14 ; PAVONE, Vincenzo15 ; TUCCI, Alessandra16 ; CORTELAZZO, Sergio17 ; LEVIS, Alessandro18 ; BOCCADORO, Mario1 ; BENEDETTI, Fabio2 ; MAJOLINO, Ignazio19 ; PILERI, Alessandro1 ; GIANNI, Alessandro M20 ; PASSERA, Roberto21 ; CORRADINI, Paolo20 ; TARELLA, Corrado1 ; VITOLO, Umberto3 ; PATTI, Caterina4 ; RAMBALDI, Alessandro5 ; PULSONI, Alessandro6 ; MUSSO, Maurizio7 ; LIBERATI, Anna M8 ; OLIVIERI, Attilio9
[1] Divisione Universitaria di Ematologia, Cattedra di Ematologia, Torino, Italy
[2] Divisione di Ematologia, Policlinico Borgo Roma, Verona, Italy
[3] Divisione Ospedaliera di Ematologia, A.O. S. Giovanni Battista, Torino, Italy
[4] Divisione di Ematologia, Ospedale V. Cervello, Palermo, Italy
[5] Divisione di Ematologia, Ospedali Riuniti, Bergamo, Italy
[6] Dipartimento di Biotecnologie Cellulari ed Ematologia, Università La Sapienza, Roma, Italy
[7] Unità operativa di Oncoematologia, Ospedale La Maddalena, Palermo, Italy
[8] Istituto di Medicina interna e Scienze oncologiche, Policlinico Monteluce, Perugia, Italy
[9] Clinica di oncologia medica, Ospedale Torrette, Ancona, Italy
[10] Divisione di Ematologia, A.O. S. Croce, Cuneo, Italy
[11] Cattedra di Medicina Interna ed Ematologia, A.O. S. Gerardo de' Tintori, Monza, Italy
[12] Cattedra Universitaria di Oncologia ed Ematologia, Istituto per la ricerca e la cura del cancro, Candiolo, Italy
[13] Divisione di Ematologia, A.O. Bianchi-Melacrino-Morelli, Reggio Calabria, Italy
[14] Cattedra di Ematologia, A.O. Ferrarotto, Catania, Italy
[15] Divisione Universitaria di Ematologia, Università degli studi di Bari, Bari, Italy
[16] Divisione di Ematologia, Ospedali Civili, Brescia, Italy
[17] Divisione di Ematologia, A.O. S. Maurizio, Bolzano/Bozen, Italy
[18] Divisione di Ematologia, A.O. S.S. Antonio e Biagio, Alessandria, Italy
[19] Divisione di Ematologia, Ospedale S. Camillo, Roma, Italy
[20] Divisione di Ematologia, Units di Trapianto di Midollo Osseo, Istituto Nazionale Tumori, Universitá di Milano, Milano, Italy
[21] Statistical Consultant, A.O. San Giovanni Battista Torino and Università di Torino, Torino, Italy
Gruppo Italiano Trapianto di Midollo Osseo (GITMO), Intergruppo Italiano Linfomi (IIL), Italy - Source
Blood. 2008, Vol 111, Num 8, pp 4004-4013, 10 p ; ref : 95 ref
- ISSN
- 0006-4971
- Scientific domain
- Medical oncology; Hematology
- Publisher
- The Americain Society of Hematology, Washington, DC
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Anticancéreux Association médicamenteuse Diagnostic Essai clinique Etude comparative Etude multicentrique Hématologie Lymphome folliculaire Prospective Randomisation Risque élevé Survie Hémopathie lymphoïde B Hémopathie maligne lymphoïde Cancer Hémopathie maligne Lymphome non hodgkinien Syndrome lymphoprolifératif
- Keyword (en)
- Antineoplastic agent Drug combination Diagnosis Clinical trial Comparative study Multicenter study Hematology Follicular lymphoma Prospective Randomization High risk Survival B cell neoplasm Lymphoid neoplasm Cancer Malignant hemopathy Non Hodgkin lymphoma Lymphoproliferative syndrome
- Keyword (es)
- Anticanceroso Asociación medicamentosa Diagnóstico Ensayo clínico Estudio comparativo Estudio multicéntrico Hematología Linfoma folicular Prospectiva Aleatorización Riesgo alto Sobrevivencia Cáncer Hemopatía maligna Linfoma no Hodgkin Linfoproliferativo síndrome
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B19 Hematologic and hematopoietic diseases / 002B19B Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis
- Discipline
- Blood diseases
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 20271058
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1182/blood-2007-10-116749 
https://dx.doi.org/10.1182/blood-2007-10-116749
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arXiv access
