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A structural analysis of the differential cytotoxicity of chemicals in the NCI-60 cancer cell lines

Author
CHAKRAVARTI, Suman K1 ; KLOPMAN, Gilles1 2
[1] Case Western Reserve University, 10900 Euclid Avenue, Cleveland, OH 44106, United States
[2] MultiCASE Inc., Suite 305, 23811 Chagrin Boulevard, Beachwood, OH 44122, United States
Source

Bioorganic & medicinal chemistry. 2008, Vol 16, Num 7, pp 4052-4063, 12 p ; ref : 39 ref

ISSN
0968-0896
Scientific domain
Biochemistry, molecular biology, biophysics; Pharmacology drugs
Publisher
Elsevier Science, Oxford
Publication country
United Kingdom
Document type
Article
Language
English
Author keyword
Anti- cancer Differential cytotoxicity MULTICASE NCI-60
Keyword (fr)
Analyse structurale Anticancéreux Carbonyle Composé organique Cellule tumorale Composé vinylique Cytotoxicité Hétérocycle azote Lignée cellulaire Modèle moléculaire Modélisation Prédiction Relation structure activité
Keyword (en)
Structural analysis Antineoplastic agent Carbonyl Organic compounds Tumor cell Vinylic compound Cytotoxicity Nitrogen heterocycle Cell line Molecular model Modeling Prediction Structure activity relation
Keyword (es)
Análisis estructural Anticanceroso Carbonilo Compuesto orgánico Célula tumoral Compuesto vinílico Citotoxicidad Heterociclo nitrógeno Línea celular Modelo molecular Modelización Predicción Relación estructura actividad
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents / 002B02R01 General aspects

Discipline
Pharmacological treatments
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
20272662

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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