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A small molecule cell-impermeant Hsp90 antagonist inhibits tumor cell motility and invasion

Author
TSUTSUMI, S1 ; SCROGGINS, B1 ; KOGA, F1 2 ; LEE, M.-J3 ; TREPEL, J3 ; FELTS, S4 5 ; CARRERAS, C2 ; NECKERS, L1
[1] Urologic Oncology Branch, National Cancer Institute, Bethesda, MD, United States
[2] Kosan Biosciences, Hayward, CA, United States
[3] Medical Oncology Branch, National Cancer Institute, Bethesda, MD, United States
[4] Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN, United States
[5] Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, United States
Source

Oncogene (Basingstoke). 2008, Vol 27, Num 17, pp 2478-2487, 10 p ; ref : 1 p

ISSN
0950-9232
Scientific domain
Cell biology, histology; Medical oncology; Genetics
Publisher
Nature Publishing, Basingstoke
Publication country
United Kingdom
Document type
Article
Language
English
Author keyword
cancer metastasis cell motility heat shock protein 90 molecularly targeted small molecules
Keyword (fr)
Antagoniste Carcinogenèse Cellule tumorale Inhibition Mouvement cellulaire Métastase Protéine choc thermique Tumeur maligne Cancer
Keyword (en)
Antagonist Carcinogenesis Tumor cell Inhibition Cell motility Metastasis Heat shock protein Malignant tumor Cancer
Keyword (es)
Antagonista Carcinogénesis Célula tumoral Inhibición Movimiento celular Metástasis Proteína choque térmico Tumor maligno Cáncer
Classification
Pascal
002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A04 Molecular and cellular biology / 002A04H Cell physiology / 002A04H04 Cell transformation and carcinogenesis. Action of oncogenes and antioncogenes

Discipline
Molecular and cell biology
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
20273822

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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