Smad3 deficiency inhibits v-ras-induced transformation by suppression of JNK MAPK signaling and increased farnesyl transferase inhibition
- Author
- ARANY, P. R1 ; RANE, S. G1 2 ; ROBERTS, A. B1
[1] Laboratory of Cell Regulation and Carcinogenesis, NCI, NIH, Bethesda, MD, United States
[2] Diabetes Branch, NIDDK, NIH, Bethesda, MD, United States - Source
Oncogene (Basingstoke). 2008, Vol 27, Num 17, pp 2507-2512, 6 p ; ref : 1 p
- ISSN
- 0950-9232
- Scientific domain
- Cell biology, histology; Medical oncology; Genetics
- Publisher
- Nature Publishing, Basingstoke
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Author keyword
- JNK MAPK Ras Smad3 TGF-β1 farnesyl transferase inhibition malignant transformation
- Keyword (fr)
- Carcinogenèse Déficit Facteur croissance transformant β1 Gène onc viral Inhibition Mitogen-activated protein kinase Protéine Smad Suppression Transformation maligne Protéine JNK Enzyme Transferases
- Keyword (en)
- Carcinogenesis Deficiency Transforming growth factor β1 V-Onc gene Inhibition Mitogen-activated protein kinase Smad protein Suppression Malignant transformation Enzyme Transferases
- Keyword (es)
- Carcinogénesis Déficiencia Factor crecimiento transformante β1 Gen onc viral Inhibición Mitogen-activated protein kinase Proteína Smad Supresión Transformación maligna Enzima Transferases
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A04 Molecular and cellular biology / 002A04H Cell physiology / 002A04H04 Cell transformation and carcinogenesis. Action of oncogenes and antioncogenes
- Discipline
- Molecular and cell biology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 20273826
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/sj.onc.1210889 
https://dx.doi.org/10.1038/sj.onc.1210889
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