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Pharmacokinetics, Efficacy, and Tolerability of Fentanyl Following Intranasal Versus Intravenous Administration in Adults Undergoing Third-Molar Extraction : A Randomized, Double-Blind, Double-Dummy, Two-Way, Crossover Study

Author
CHRISTRUP, Lona L1 ; FOSTER, David2 ; POPPER, Lars D3 ; TROEN, Tine4 ; UPTON, Richard5
[1] Department of Pharmacology and Pharmacotherapy, Faculty of Pharmaceutical Sciences, University of Copenhagen, Copenhagen, Denmark
[2] Sansom Institute, School of Pharmacy and Medical Sciences, University of South Australia, Adelaide, Australia
[3] Department of Medical Scientific Strategy and Medical Marketing, Nycomed Pharma, Roskilde, Denmark
[4] Department of Biostatistics, Nycomed Pharma, Roskilde, Denmark
[5] Discipline of Anaesthesia and Intensive Care, Royal Adelaide Hospital, The University of Adelaide, Adelaide, Australia
Source

Clinical therapeutics. 2008, Vol 30, Num 3, pp 469-481, 13 p ; ref : 30 ref

ISSN
0149-2918
Scientific domain
Pharmacology drugs
Publisher
Excerpta Medica, Belle Mead, NJ
Publication country
United States
Document type
Article
Language
English
Author keyword
efficacy intranasal fentanyl pharmacokinetics tolerability
Keyword (fr)
Adulte Analgésique narcotique Efficacité traitement Essai croisé Etude comparative Etude double insu Extraction Fentanyl Pharmacocinétique Randomisation Toxicité Troisième molaire Voie intranasale Voie intraveineuse Agoniste Dent Homme Opiacés Phénylpipéridine dérivé Récepteur opiacé μ
Keyword (en)
Adult Narcotic analgesic Treatment efficiency Crossover study Comparative study Double blind study Extraction Fentanyl Pharmacokinetics Randomization Toxicity Third molar tooth Intranasal administration Intravenous administration Agonist Tooth Human Opiates Phenylpiperidine derivatives μ Opioid receptor
Keyword (es)
Adulto Analgésico narcotico Eficacia tratamiento Ensayo cruzado Estudio comparativo Estudio doble ciego Extracción Fentanilo Farmacocinética Aleatorización Toxicidad Tercer molar Vía intranasal Vía intravenosa Agonista Diente Hombre Opiados fenilpiperidine derivado Receptor opiáceo μ
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments

Discipline
General pharmacology
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
20277103

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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