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A phase II study of patients with metastatic or locoregionally recurrent nasopharyngeal carcinoma and evaluation of plasma Epstein-Barr virus DNA as a biomarker of efficacy

MA, Brigette1 ; HUI, Edwin P1 2 ; AHUJA, Anil3 ; CHAN, Anthony T. C1 2 ; KING, Ann3 ; TO, K. F2 4 ; MO, Frankie1 ; LEUNG, Sing F1 2 ; KAM, Michael1 ; LO, Y. M. Dennis2 5 6 ; ZEE, Benny1 ; MOK, Tony1 2
[1] Department of Clinical Oncology and Sir Y.K. Pao Cancer Center, Prince of Wales Hospital, Shatin, Hong-Kong
[2] State Key Laboratory of Southern China, Chinese University of Hong Kong, Shatin, Hong-Kong
[3] Department of Diagnostic Imaging and Organ Imaging, Prince of Wales Hospital, Shatin, Hong-Kong
[4] Department of Anatomical and Cellular Pathology, Prince of Wales Hospital, Shatin, Hong-Kong
[5] Department of Chemical Pathology, Prince of Wales Hospital, Shatin, Hong-Kong
[6] Li Ka Shing Institute of Health Sciences, Prince of Wales Hospital, Chinese University of Hong Kong, Shatin, Hong-Kong

Cancer chemotherapy and pharmacology. 2008, Vol 62, Num 1, pp 59-64, 6 p ; ref : 37 ref

Scientific domain
Medical oncology; Pharmacology drugs
Springer, Berlin
Publication country
Document type
Author keyword
Epidermal growth factor receptor Gefitinib Nasopharyngeal carcinoma Plasma EBV DNA
Keyword (fr)
Anticancéreux Cancer du nasopharynx Carcinome du nasopharynx DNA Efficacité traitement Essai clinique phase II Evaluation Géfitinib Homme Liquide biologique Marqueur biologique Métastase Plasma sanguin Récepteur facteur croissance épiderme Récepteur facteur croissance Récidive Stade avancé Traitement Virose Virus Epstein Barr Cancer Dérivé de la quinazoline Enzyme Gammaherpesvirinae Herpesviridae Infection Inhibiteur de la tyrosine kinase Inhibiteur enzyme Pathologie ORL Pathologie du pharynx Protein-tyrosine kinase Transferases Tumeur maligne Virus
Keyword (en)
Antineoplastic agent Nasopharynx cancer Nasopharynx carcinoma DNA Treatment efficiency Phase II trial Evaluation Gefitinib Human Biological fluid Biological marker Metastasis Blood plasma Epidermal growth factor receptor Growth factor receptor Relapse Advanced stage Treatment Viral disease Epstein Barr virus Cancer Quinazoline derivatives Enzyme Gammaherpesvirinae Herpesviridae Infection Tyrosine kinase inhibitor Enzyme inhibitor ENT disease Pharynx disease Protein-tyrosine kinase Transferases Malignant tumor Virus
Keyword (es)
Anticanceroso Cáncer del nasopharynx Carcinoma nasofaringe DNA Eficacia tratamiento Ensayo clínico fase II Evaluación Gefitinib Hombre Líquido biológico Marcador biológico Metástasis Plasma sanguíneo Receptor del factor de crecimiento epidérmico Receptor factor crecimiento Recaida Estadio avanzado Tratamiento Virosis Epstein Barr virus Cáncer Enzima Gammaherpesvirinae Herpesviridae Infección Inhibidor tyrosine kinase Inhibidor enzima ORL patología Faringe patología Protein-tyrosine kinase Transferases Tumor maligno Virus
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents

002 Biological and medical sciences / 002B Medical sciences / 002B05 Infectious diseases / 002B05C Viral diseases

002 Biological and medical sciences / 002B Medical sciences / 002B10 Otorhinolaryngology. Stomatology / 002B10B Upper respiratory tract, upper alimentary tract, paranasal sinuses, salivary glands: diseases, semeiology / 002B10B01 Tumors

Infectious pathology Otorhinolaryngology. Stomatology Pharmacological treatments
INIST identifier

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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