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Akt activation protects pancreatic beta cells from AMPK-mediated death through stimulation of mTOR

Author
YING CAI1 ; QIDI WANG1 ; ZHIDONG LING1 ; PIPELEERS, Daniel1 ; MCDERMOTT, Paul2 3 ; PENDE, Mario4 ; HEIMBERG, Harry1 ; VAN DE CASTEELE, Mark1
[1] Diabetes Research Center, Brussels Free University, VUB, Partner of the Juvénile Diabetes Research Center for Beta Cell Therapy in Europe, Laarbeeklaan 103, 1090 Brussels, Belgium
[2] Department of Medicine, the Gazes Cardiac Research Institute, Medical University of South Carolina, United States
[3] Ralph H. Johnson Department of Veterans Affairs Medical Center, Charleston, SC 29403, United States
[4] Inserm, Avenir, U584, Université Paris 5, Faculté de Médecine Necker-Enfants Malades, 156 rue de Vaugirard, Paris 75730, France
Source

Biochemical pharmacology. 2008, Vol 75, Num 10, pp 1981-1993, 13 p ; ref : 54 ref

CODEN
BCPCA6
ISSN
0006-2952
Scientific domain
Biochemistry, molecular biology, biophysics; Pharmacology drugs; Physiology, morphology
Publisher
Elsevier Science, New York, NY
Publication country
United States
Document type
Article
Language
English
Author keyword
AMPK Akt Apoptosis Beta cell Diabetes mTOR
Keyword (fr)
Akt protein kinase Apoptose Cellule β Diabète Mort cellulaire Protéine mTOR Prévention Stimulation cAMP-dependent protein kinase Protein kinase mTOR Endocrinopathie Pancréas endocrine
Keyword (en)
Akt protein kinase Apoptosis β Cell Diabetes mellitus Cell death Mammalian target of rapamycin Prevention Stimulation cAMP-dependent protein kinase Protein kinase mTOR Endocrinopathy Endocrine pancreas
Keyword (es)
Akt protein kinase Apoptosis Célula β Diabetes Muerte celular Proteína mTOR Prevención Estimulación cAMP-dependent protein kinase Endocrinopatía Páncreas endocrino
Classification
Pascal
002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A04 Molecular and cellular biology / 002A04H Cell physiology / 002A04H05 Ageing, cell death

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B21 Endocrinopathies / 002B21E Endocrine pancreas. Apud cells (diseases) / 002B21E01 Diabetes. Impaired glucose tolerance / 002B21E01A Etiopathogenesis. Screening. Investigations. Target tissue resistance

Discipline
Endocrinopathies Molecular and cell biology
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
20317446

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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