Synthesis, cytotoxic activity, and SAR analysis of the derivatives of taxchinin A and brevifoliol
- Author
- YU ZHAO1 ; NA GUO1 ; LOU, Li-Guang2 ; CONG, Yu-Wen3 ; PENG, Li-Yan1 ; ZHAO, Qin-Shi1
[1] State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, China
[2] Shanghai Institute of Materia Medica, Shanghai Institute for Biological Science, Chinese Academy of Sciences, Shanghai 200032, China
[3] Institute of Radiation Medicine, Academy of Military Medical Sciences, Beijing 100850, China - Source
Bioorganic & medicinal chemistry. 2008, Vol 16, Num 9, pp 4860-4871, 12 p ; ref : 17 ref
- ISSN
- 0968-0896
- Scientific domain
- Biochemistry, molecular biology, biophysics; Pharmacology drugs
- Publisher
- Elsevier Science, Oxford
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Author keyword
- Cytotoxicity Derivatives of taxchinin A and brevifoliol SAR Synthesis
- Keyword (fr)
- Cellule tumorale Cytotoxicité Diterpène Homme In vitro Lignée cellulaire Méthode CoMFA Poumon Prédiction Relation structure activité Synthèse chimique Terpénoïde 11(15→1) abéo Taxane dérivé Brévifoliol Lignée A549 Taxchinine A
- Keyword (en)
- Tumor cell Cytotoxicity Diterpene Human In vitro Cell line Comparative molecular field analysis method Lung Prediction Structure activity relation Chemical synthesis Terpenoid
- Keyword (es)
- Célula tumoral Citotoxicidad Diterpeno Hombre In vitro Línea celular Método CoMFA Pulmón Predicción Relación estructura actividad Síntesis química Terpenoide
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents / 002B02R01 General aspects
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 20351202
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.bmc.2008.03.041 
https://dx.doi.org/10.1016/j.bmc.2008.03.041
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