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The Albumin Effect and Drug Glucuronidation : Bovine Serum Albumin and Fatty Acid-Free Human Serum Albumin Enhance the Glucuronidation of UDP-Glucuronosyltransferase (UGT) 1A9 Substrates but Not UGT1A1 and UGT1A6 Activities

Author
ROWLAND, Andrew1 ; KNIGHTS, Kathleen M1 ; MACKENZIE, Peter I1 ; MINERS, John O1
[1] Department of Clinical Pharmacology, Flinders University and Flinders Medical Centre, Bedford Park, Adelaide, Australia
Source

Drug metabolism and disposition. 2008, Vol 36, Num 6, pp 1056-1062, 7 p ; ref : 3/4 p

CODEN
DMDSAI
ISSN
0090-9556
Scientific domain
Pharmacology drugs
Publisher
American Society for Pharmacology and Experimental Therapeutics, Bethesda, MD
Publication country
United States
Document type
Article
Language
English
Keyword (fr)
Acide gras libre Activité biologique Albumine Animal Boeuf Bovin Glucuroconjugaison Homme Isozyme Médicament Substrat Sérumalbumine UDP-glucuronosyltransferase Artiodactyla Enzyme Glycosyltransferases Hexosyltransferases Lipide Mammalia Métabolisme Pharmacocinétique Transferases Ungulata Vertebrata
Keyword (en)
Free fatty acid Biological activity Albumin Animal Ox Bovine Glucuronic acid conjugation Human Isozyme Drug Substrate Serum albumin UDP-glucuronosyltransferase Artiodactyla Enzyme Glycosyltransferases Hexosyltransferases Lipids Mammalia Metabolism Pharmacokinetics Transferases Ungulata Vertebrata
Keyword (es)
Acido graso libre Actividad biológica Albúmina Animal Buey Bovino Glucuroconjugación Hombre Isozima Medicamento Substrato Seroalbúmina UDP-glucuronosyltransferase Artiodactyla Enzima Glycosyltransferases Hexosyltransferases Lípido Mammalia Metabolismo Farmacocinética Transferases Ungulata Vertebrata
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments

Discipline
General pharmacology
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
20358813

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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