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Alterations in S-adenosylhomocysteine metabolism decrease O6-methylguanine DNA methyltransferase gene expression without affecting promoter methylation

Author
HERMES, Marina1 ; GEISLER, Hermann1 ; OSSWALD, Hartmut1 ; RIEHLE, Renate1 ; KLOOR, Doris1
[1] Department of Pharmacology and Toxicology, Faculty of Medicine, University of Tübingen, Wilhelmstrasse 56, 72074 Tübingen, Germany
Source

Biochemical pharmacology. 2008, Vol 75, Num 11, pp 2100-2111, 12 p ; ref : 77 ref

CODEN
BCPCA6
ISSN
0006-2952
Scientific domain
Biochemistry, molecular biology, biophysics; Pharmacology drugs; Physiology, morphology
Publisher
Elsevier Science, New York, NY
Publication country
United States
Document type
Article
Language
English
Author keyword
O6-Methylguanine DNA methyltransferase;Promoter methylation;S-Adenosylhomocysteine hydrolase;DNA methylation;mRNA methylation
Keyword (fr)
DNA Expression génique Methylated-DNA-protein-cysteine S-methyltransferase Métabolisme Méthylation Promoteur transcription Guanine(6-O-méthyl) Enzyme Methyltransferases Pharmacocinétique Transferases
Keyword (en)
DNA Gene expression Methylated-DNA-protein-cysteine S-methyltransferase Metabolism Methylation Transcription promoter Enzyme Methyltransferases Pharmacokinetics Transferases
Keyword (es)
DNA Expresión genética Methylated-DNA-protein-cysteine S-methyltransferase Metabolismo Metilación Promotor transcripción Enzima Methyltransferases Farmacocinética Transferases
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments

Discipline
General pharmacology
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
20361912

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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