A phase II trial of lomeguatrib and temozolomide in metastatic colorectal cancer
- Author
- KHAN, O. A1 ; RANSON, M2 ; MICHAEL, M3 ; OLVER, I4 ; LEVITT, N. C1 ; MORTIMER, P5 ; WATSON, A. J6 ; MARGISON, G. P6 ; MIDGLEY, R1 ; MIDDLETON, M. R1
[1] CR UK Medical Oncology Unit Churchill Hospital, Old Road, Oxford OX3 7LJ, United Kingdom
[2] Department of Medical Oncology, University of Manchester, Christie Hospital, Wilmslow Road, Manchester M20 9BX, United Kingdom
[3] Department of Hematology and Medical Oncology, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia
[4] Royal Adelaide Hospital, Adelaide, South Australia, Australia
[5] Kudos Pharmaceuticals Ltd, 327 Cambridge Science Park, Milton Road, Cambridge CB4 OWG, United Kingdom
[6] CR UK Carcinogenesis Group, Paterson Institute for Cancer Research, Wilmslow Road, Manchester M20 4BX, United Kingdom - Source
British journal of cancer. 2008, Vol 98, Num 10, pp 1614-1618, 5 p ; ref : 3/4 p
- CODEN
- BJCAAI
- ISSN
- 0007-0920
- Scientific domain
- Medical oncology
- Publisher
- Nature Publishing Group, Basingstoke
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Author keyword
- DNA repair O6-methylguanine-DNA methyltransferase colorectal cancer lomeguatrib temozolomide
- Keyword (fr)
- Anticancéreux Cancer colorectal Cancérologie DNA Essai clinique phase II Lomeguatrib Methylated-DNA-protein-cysteine S-methyltransferase Métastase Stade avancé Témozolomide Alkyltransferase des alkylguanines Réparation DNA Agent alkylant Cancer Enzyme Inhibiteur enzyme Methyltransferases Pathologie de l'appareil digestif Pathologie de l'intestin Pathologie du côlon Pathologie du rectum Transferases Tumeur maligne
- Keyword (en)
- Antineoplastic agent Colorectal cancer Cancerology DNA Phase II trial Lomeguatrib Methylated-DNA-protein-cysteine S-methyltransferase Metastasis Advanced stage Temozolomide DNA repair Alkylating agent Cancer Enzyme Enzyme inhibitor Methyltransferases Digestive diseases Intestinal disease Colonic disease Rectal disease Transferases Malignant tumor
- Keyword (es)
- Anticanceroso Cancer de colon y recto Cancerología DNA Ensayo clínico fase II Lomeguatrib Methylated-DNA-protein-cysteine S-methyltransferase Metástasis Estadio avanzado Temozolomida Agente alquilante Cáncer Enzima Inhibidor enzima Methyltransferases Aparato digestivo patología Intestino patología Colón patología Recto patología Transferases Tumor maligno
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B13 Gastroenterology. Liver. Pancreas. Abdomen / 002B13B Stomach. Duodenum. Small intestine. Colon. Rectum. Anus / 002B13B01 Tumors
- Discipline
- Gastroenterology. Liver. Pancreas. Abdomen Tumours
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 20374133
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/sj.bjc.6604366 
https://dx.doi.org/10.1038/sj.bjc.6604366
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