A novel histone deacetylase 8 (HDAC8)-specific inhibitor PCI-34051 induces apoptosis in T-cell lymphomas
- Author
- BALASUBRAMANIAN, S1 ; RAMOS, J1 ; LUO, W2 ; SIRISAWAD, M1 ; VERNER, E2 ; BUGGY, J. J1
[1] Department of Cancer Biology, Pharmacyclics Inc, Sunnyvale, CA, United States
[2] Department of Chemistry, Pharmacyclics Inc, Sunnyvale, CA, United States - Source
Leukemia. 2008, Vol 22, Num 5, pp 1026-1034, 9 p ; ref : 50 ref
- CODEN
- LEUKED
- ISSN
- 0887-6924
- Scientific domain
- Medical oncology; Hematology
- Publisher
- Nature Publishing, London
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Author keyword
- HDAC isoform-specific inhibitors T-cell signaling calcium-induced apoptosis phospholipase C-γ1 protein acetylation
- Keyword (fr)
- Acétylation Apoptose Calcium Forme moléculaire Hématologie Inhibiteur histone deacetylase Lymphocyte T Mort cellulaire Phospholipase C Protéine Transduction signal Lymphome T Elément minéral Enzyme Esterases Hydrolases Phosphoric diester hydrolases
- Keyword (en)
- Acetylation Apoptosis Calcium Molecular form Hematology Histone deacetylase inhibitor T-Lymphocyte Cell death Phospholipase C Protein Signal transduction T lymphoma Inorganic element Enzyme Esterases Hydrolases Phosphoric diester hydrolases
- Keyword (es)
- Acetilación Apoptosis Calcio Forma molecular Hematología Inhibidor histone deacetylase Linfocito T Muerte celular Phospholipase C Proteína Transducción señal Elemento inorgánico Enzima Esterases Hydrolases Phosphoric diester hydrolases
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B19 Hematologic and hematopoietic diseases
- Discipline
- Blood diseases
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 20378647
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/leu.2008.9 
https://dx.doi.org/10.1038/leu.2008.9
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