Agomelatine, a melatonin receptor agonist with 5-HT2C receptor antagonist properties, protects the developing murine white matter against excitotoxicity
- Author
- GRESSENS, Pierre1 2 3 4 ; SCHWENDIMANN, Leslie1 2 4 ; HUSSON, Isabelle1 2 3 4 ; SARKOZY, Gergely5 ; MOCAER, Elizabeth6 ; VAMECQ, Joseph7 ; SPEDDING, Michael6
[1] Inserrn, U676, Paris, 75019, France
[2] Université Paris 7, Faculté de Médecine Denis Diderot, IFR02 and IFR25, Paris, France
[3] AP HP, Hôpital Robert Debré, Service de Neurologie Pédiatrique, Paris, France
[4] PremUP, Paris, France
[5] Department of Neonatology, Medical University Innsbruck, Innsbruck, Austria
[6] Institut de Recherches Servier (IdRS), 11 Rue des Moulineaux, 92150, Suresnes, France
[7] Inserm UNIV 045131, Neuropédiatrie. Hôpital Salengro, CHRU, Lille, France - Source
European journal of pharmacology. 2008, Vol 588, Num 1, pp 58-63, 6 p ; ref : 3/4 p
- CODEN
- EJPHAZ
- ISSN
- 0014-2999
- Scientific domain
- Pharmacology drugs
- Publisher
- Elsevier, Amsterdam
- Publication country
- Netherlands
- Document type
- Article
- Language
- English
- Author keyword
- Agomelatine Cerebral palsy Ibotenate N-methyl-d-aspartate Periventricular leukomalacia
- Keyword (fr)
- Agomélatine Agoniste Animal Antagoniste Développement Excitotoxicité Infirmité motrice cérébrale Leucomalacie périventriculaire NMDA Prévention Récepteur mélatonine Récepteur sérotoninergique 5-HT2C Souris Substance blanche Analogue Hormone épiphysaire Mammalia Mélatonine Pathologie cérébrovasculaire Pathologie de l'appareil circulatoire Pathologie de l'encéphale Pathologie des vaisseaux sanguins Pathologie du système nerveux central Pathologie du système nerveux Ramollissement cérébral Rodentia Toxicité Vertebrata
- Keyword (en)
- Agomelatine Agonist Animal Antagonist Development Excitotoxicity Cerebral palsy Periventricular leukomalacia NMDA Prevention Melatonin receptor 5-HT2C serotonin receptor Mouse White matter Analog Pineal hormone Mammalia Melatonin Cerebrovascular disease Cardiovascular disease Cerebral disorder Vascular disease Central nervous system disease Nervous system diseases Cerebral infarction Rodentia Toxicity Vertebrata
- Keyword (es)
- Agomelatina Agonista Animal Antagonista Desarrollo Exitotoxicidad Encefalopatía infantil Leucomalacia periventricular NMDA Prevención Receptor melatonina Receptor serotoninérgico 5-HT2C Ratón Substancia blanca Análogo Hormona epifisaria Mammalia Melatonina Vaso sanguíneo encéfalo patología Aparato circulatorio patología Encéfalo patología Vaso sanguíneo patología Sistema nervosio central patología Sistema nervioso patología Infarto cerebral Rodentia Toxicidad Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B17 Neurology / 002B17A Nervous system (semeiology, syndromes) / 002B17A03 Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B17 Neurology / 002B17C Vascular diseases and vascular malformations of the nervous system
- Discipline
- General pharmacology Neurology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 20392829
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.ejphar.2008.04.016 
https://dx.doi.org/10.1016/j.ejphar.2008.04.016
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