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Agomelatine, a melatonin receptor agonist with 5-HT2C receptor antagonist properties, protects the developing murine white matter against excitotoxicity

Author
GRESSENS, Pierre1 2 3 4 ; SCHWENDIMANN, Leslie1 2 4 ; HUSSON, Isabelle1 2 3 4 ; SARKOZY, Gergely5 ; MOCAER, Elizabeth6 ; VAMECQ, Joseph7 ; SPEDDING, Michael6
[1] Inserrn, U676, Paris, 75019, France
[2] Université Paris 7, Faculté de Médecine Denis Diderot, IFR02 and IFR25, Paris, France
[3] AP HP, Hôpital Robert Debré, Service de Neurologie Pédiatrique, Paris, France
[4] PremUP, Paris, France
[5] Department of Neonatology, Medical University Innsbruck, Innsbruck, Austria
[6] Institut de Recherches Servier (IdRS), 11 Rue des Moulineaux, 92150, Suresnes, France
[7] Inserm UNIV 045131, Neuropédiatrie. Hôpital Salengro, CHRU, Lille, France
Source

European journal of pharmacology. 2008, Vol 588, Num 1, pp 58-63, 6 p ; ref : 3/4 p

CODEN
EJPHAZ
ISSN
0014-2999
Scientific domain
Pharmacology drugs
Publisher
Elsevier, Amsterdam
Publication country
Netherlands
Document type
Article
Language
English
Author keyword
Agomelatine Cerebral palsy Ibotenate N-methyl-d-aspartate Periventricular leukomalacia
Keyword (fr)
Agomélatine Agoniste Animal Antagoniste Développement Excitotoxicité Infirmité motrice cérébrale Leucomalacie périventriculaire NMDA Prévention Récepteur mélatonine Récepteur sérotoninergique 5-HT2C Souris Substance blanche Analogue Hormone épiphysaire Mammalia Mélatonine Pathologie cérébrovasculaire Pathologie de l'appareil circulatoire Pathologie de l'encéphale Pathologie des vaisseaux sanguins Pathologie du système nerveux central Pathologie du système nerveux Ramollissement cérébral Rodentia Toxicité Vertebrata
Keyword (en)
Agomelatine Agonist Animal Antagonist Development Excitotoxicity Cerebral palsy Periventricular leukomalacia NMDA Prevention Melatonin receptor 5-HT2C serotonin receptor Mouse White matter Analog Pineal hormone Mammalia Melatonin Cerebrovascular disease Cardiovascular disease Cerebral disorder Vascular disease Central nervous system disease Nervous system diseases Cerebral infarction Rodentia Toxicity Vertebrata
Keyword (es)
Agomelatina Agonista Animal Antagonista Desarrollo Exitotoxicidad Encefalopatía infantil Leucomalacia periventricular NMDA Prevención Receptor melatonina Receptor serotoninérgico 5-HT2C Ratón Substancia blanca Análogo Hormona epifisaria Mammalia Melatonina Vaso sanguíneo encéfalo patología Aparato circulatorio patología Encéfalo patología Vaso sanguíneo patología Sistema nervosio central patología Sistema nervioso patología Infarto cerebral Rodentia Toxicidad Vertebrata
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B17 Neurology / 002B17A Nervous system (semeiology, syndromes) / 002B17A03 Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B17 Neurology / 002B17C Vascular diseases and vascular malformations of the nervous system

Discipline
General pharmacology Neurology
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
20392829

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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