A phase I study of docetaxel with ketoconazole modulation in patients with advanced cancers
- Author
- YONG, Wei-Peng1 ; WANG, Ling-Zhi1 2 ; THAM, Lai-San1 ; WONG, Chiung-Ing1 ; LEE, Soo-Chin1 ; SOO, Ross1 ; SUKRI, Norita1 ; LEE, How-Sung2 ; GOH, Boon-Cher2
[1] Cancer Therapeutics Research Group, Department of Haematology-Oncology, National University Hospital, 5 Lower Kent Ridge Road, Singapore, Singapore 119074, Singapore
[2] Department of Pharmacology, National University of Singapore, Singapore, Singapore 119074, Singapore - Source
Cancer chemotherapy and pharmacology. 2008, Vol 62, Num 2, pp 243-251, 9 p ; ref : 35 ref
- CODEN
- CCPHDZ
- ISSN
- 0344-5704
- Scientific domain
- Medical oncology; Pharmacology drugs
- Publisher
- Springer, Berlin
- Publication country
- Germany
- Document type
- Article
- Language
- English
- Author keyword
- CYP3A Docetaxel . Ketoconazole Midazolam . Pharmacokinetic
- Keyword (fr)
- Anticancéreux Cytochrome P450 Docétaxel Essai clinique phase I Homme Isozyme Kétoconazole Midazolam Modulation Pharmacocinétique Stade avancé Traitement Tumeur maligne Cytochrome P450 3A Antimitotique Cancer Dérivé de l'imidazole Dérivé de la benzodiazépine Dérivé du taxane Enzyme
- Keyword (en)
- Antineoplastic agent Cytochrome P450 Docetaxel Phase I trial Human Isozyme Ketoconazole Midazolam Modulation Pharmacokinetics Advanced stage Treatment Malignant tumor Antimitotic Cancer Imidazole derivatives Benzodiazepine derivatives Taxane derivatives Enzyme
- Keyword (es)
- Anticanceroso Citocromo P450 Docetaxel Ensayo clínico fase I Hombre Isozima Ketoconazol Midazolam Modulación Farmacocinética Estadio avanzado Tratamiento Tumor maligno Antimitótico Cáncer Imidazol derivado Benzodiazepina derivado Taxane derivado Enzima
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 20404674
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1007/s00280-007-0598-1 
https://dx.doi.org/10.1007/s00280-007-0598-1
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