Specificity, affinity and efficacy of iota-conotoxin RXIA, an agonist of voltage-gated sodium channels Nav1.2, 1.6 and 1.7
- Author
- FIEDLER, Brian1 ; ZHANG, Min-Min1 ; BUCZEK, Oga1 ; AZAM, Layla1 ; BULAJ, Grzegorz2 ; NORTON, Raymond S3 ; OLIVERA, Baldomero M1 ; YOSHIKAMI, Doju1
[1] Department of Biology, University of Utah, Salt Lake City, Utah 84112, United States
[2] Department of Medicinal Chemistry, University of Utah, Salt Lake City, Utah 84108, United States
[3] The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville 3050, Australia - Source
Biochemical pharmacology. 2008, Vol 75, Num 12, pp 2334-2344, 11 p ; ref : 46 ref
- CODEN
- BCPCA6
- ISSN
- 0006-2952
- Scientific domain
- Biochemistry, molecular biology, biophysics; Pharmacology drugs; Physiology, morphology
- Publisher
- Elsevier Science, New York, NY
- Publication country
- United States
- Document type
- Article
- Language
- English
- Author keyword
- Channel-activation;Conopeptide;Excitotoxin;Iota-conotoxin RXIA;Neurotoxin;Voltage-gated sodium channel
- Keyword (fr)
- Affinité Agoniste Canal ionique Efficacité traitement Gating Sodium Spécificité Conotoxine
- Keyword (en)
- Affinity Agonist Ionic channel Treatment efficiency Gating Sodium Specificity Conotoxin
- Keyword (es)
- Afinidad Agonista Canal iónico Eficacia tratamiento Gating Sodio Especificidad
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments
- Discipline
- General pharmacology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 20410942
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.bcp.2008.03.019 
https://dx.doi.org/10.1016/j.bcp.2008.03.019
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