Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension
- Author
- UEHATA, M1 ; ISHIZAKI, T2 ; NARUMIYA, S2 ; SATOH, H1 ; ONO, T1 ; KAWAHARA, T1 ; MORISHITA, T1 ; TAMAKAWA, H1 ; YAMAGAMI, K1 ; INUI, J1 ; MAEKAWA, M2
[1] Discovery Research (Tokyo), Yoshitomi Pharmaceutical Industries Ltd, Iruma, Saitama 358, Japan
[2] Department of Pharmacology, Faculty of Medicine, Kyoto University, Yoshida, Kyoto 606-01, Japan - Source
Nature (London). 1997, Vol 389, Num 6654, pp 990-994 ; ref : 29 ref
- CODEN
- NATUAS
- ISSN
- 0028-0836
- Scientific domain
- Multidisciplinary
- Publisher
- Nature Publishing, London
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Animal Antihypertenseur Aorte Calcium ion Chimiothérapie Fixation biologique Hypertension artérielle In vitro In vivo Interaction moléculaire Isozyme Muscle lisse Mécanisme action Protein kinase Pyridine dérivé Rat Traitement Vaisseau sanguin Voie orale Y 27632 p160ROCK Appareil circulatoire pathologie Enzyme Mammalia Rodentia Transferases Vertebrata
- Keyword (en)
- Animal Antihypertensive agent Aorta Calcium ion Chemotherapy Biological fixation Hypertension In vitro In vivo Molecular interaction Isozyme Smooth muscle Mechanism of action Protein kinase Pyridine derivatives Rat Treatment Blood vessel Oral administration Cardiovascular disease Enzyme Mammalia Rodentia Transferases Vertebrata
- Keyword (es)
- Animal Antihipertensivo Aorta Calcio ión Quimioterapia Fijación biológica Hipertensión arterial In vitro In vivo Interacción molecular Isozima Músculo liso Mecanismo acción Protein kinase Piridina derivado Rata Tratamiento Vaso sanguíneo Vía oral Aparato circulatorio patología Enzima Mammalia Rodentia Transferases Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02F Cardiovascular system / 002B02F05 Antihypertensive agents
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 2044203
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/40187 
https://dx.doi.org/10.1038/40187
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