ARIMOCLOMOL AT DOSAGES UP TO 300 MG/DAY IS WELL TOLERATED AND SAFE IN AMYOTROPHIC LATERAL SCLEROSIS
- Author
- CUDKOWICZ, Merit E1 ; SHEFNER, Jeremy M2 ; BARBER, Jack R5 ; SIMPSON, Elizabeth1 ; GRASSO, Daniela1 ; HONG YU1 ; HUI ZHANG3 ; SHUI, Amy3 ; SCHOENFELD, David3 ; BROWN, Robert H4 ; WIELAND, Scott5
[1] Neurology Clinical Trials Unit, Massachusetts General Hospital, Building 149, 13th Street, Room 2274, Charlestown, Massachusetts 02129, United States
[2] SUNY Upstate Medical University, Syracuse, New York, United States
[3] Department of Biostatistics, Massachusetts General Hospital, Boston, Massachusetts, United States
[4] Day Laboratory, Massachusetts General Hospital, Charlestown, Massachusetts, United States
[5] CytRx Corporation, Los Angeles, California, United States
NORTHEAST ALS CONSORTIUM, United States - Source
Muscle & nerve. 2008, Vol 38, Num 1, pp 837-844, 8 p ; ref : 27 ref
- CODEN
- MUNEDE
- ISSN
- 0148-639X
- Scientific domain
- Neurology; Physiology, morphology
- Publisher
- Wiley, New York, NY
- Publication country
- United States
- Document type
- Article
- Language
- English
- Author keyword
- amyotrophic lateral sclerosis arimoclomol clinical trial protein aggregation
- Keyword (fr)
- Choc Essai clinique Homme Liquide céphalorachidien Pharmacocinétique Protéine Sclérose latérale amyotrophique Stress Sécurité Sérum Traitement Maladie dégénérative Pathologie de la moelle épinière Pathologie du système nerveux central Pathologie du système nerveux
- Keyword (en)
- Shock Clinical trial Human Cerebrospinal fluid Pharmacokinetics Protein Amyotrophic lateral sclerosis Stress Safety Serum Treatment Degenerative disease Spinal cord disease Central nervous system disease Nervous system diseases
- Keyword (es)
- Choque Ensayo clínico Hombre Líquido cefalorraquídeo Farmacocinética Proteína Esclerosis lateral amiotrófica Estrés Seguridad Suero Tratamiento Enfermedad degenerativa Médula espinal patología Sistema nervosio central patología Sistema nervioso patología
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B17 Neurology / 002B17G Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases
- Discipline
- Neurology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 20460682
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1002/mus.21059 
https://dx.doi.org/10.1002/mus.21059
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