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Age-related decline in mitochondrial DNA copy number in isolated human pancreatic islets

Author
CREE, L. M1 ; PATEL, S. K2 ; PYLE, A1 ; LYNN, S3 ; TURNBULL, D. M1 ; CHINNERY, P. F1 ; WALKER, M4
[1] Mitochondrial Research Group, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom
[2] Department of Medicine, Cardiovascular Research Group, University of Melbourne, Melbourne, Australia
[3] Institute of Human Genetics, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom
[4] Diabetes Research Group, School of Clinical Medical Sciences, Faculty of Medical Sciences, Newcastle University, Medical School, Framlington Place, Newcastle upon Tyne NE2 4HH, United Kingdom
Source

Diabetologia (Berlin). 2008, Vol 51, Num 8, pp 1440-1443, 4 p ; ref : 12 ref

ISSN
0012-186X
Scientific domain
Endocrinology; Nutrition, obesity, metabolic disorders
Publisher
Springer, Berlin
Publication country
Germany
Document type
Article
Language
English
Author keyword
Ageing Human islets Mitochondrial DNA copy number Mitochondrial DNA deletion Mitochondrial DNA depletion Pancreatic beta cell function
Keyword (fr)
Age Cellule β DNA mitochondrial Diabète Délétion Déplétion Homme Ilot Langerhans Sénescence Vieillissement Endocrinopathie Pancréas endocrine
Keyword (en)
Age β Cell Mitochondrial DNA Diabetes mellitus Deletion Depletion Human Langerhans islet Senescence Ageing Endocrinopathy Endocrine pancreas
Keyword (es)
Edad Célula β DNA mitocondrial Diabetes Deleción Depleción Hombre Isla Langerhans Senescencia Envejecimiento Endocrinopatía Páncreas endocrino
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B21 Endocrinopathies / 002B21E Endocrine pancreas. Apud cells (diseases) / 002B21E01 Diabetes. Impaired glucose tolerance / 002B21E01A Etiopathogenesis. Screening. Investigations. Target tissue resistance

Discipline
Endocrinopathies
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
20487414

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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