Species Differences in Inhibition Potential of Nonsteroidal Anti-Inflammatory Drugs against Estradiol 3β-Glucuronidation between Rats, Dogs, and Humans
- Author
- MANO, Yuji1 ; USUI, Takashi1 ; KAMIMURA, Hidetaka1
[1] Drug Metabolism Research Laboratories, Astellas Pharma, Inc., 1-8, Azusawa 1-Chome, Itabashi-ku, Tokyo 174-8511, Japan - Source
Journal of pharmaceutical sciences. 2008, Vol 97, Num 7, pp 2805-2810, 6 p ; ref : 15 ref
- CODEN
- JPMSAE
- ISSN
- 0022-3549
- Scientific domain
- Pharmacology drugs
- Publisher
- American Pharmaceutical Association, Washington, DC
/
Wiley, Hoboken, NJ
- Publication country
- United States
- Document type
- Article
- Language
- English
- Author keyword
- drug interactions glucuronosyltransferases (UGT) inhibition metabolite kinetics microsomes
- Keyword (fr)
- Animal Antiinflammatoire non stéroïde Chien Cinétique Espèce Estradiol Glucuroconjugaison Homme In vitro Interaction médicamenteuse Microsome Métabolite Oestrogène Rat Technologie pharmaceutique UDP-glucuronosyltransferase Carnivora Enzyme Fissipedia Glycosyltransferases Hexosyltransferases Mammalia Métabolisme Pharmacocinétique Rodentia Transferases Vertebrata
- Keyword (en)
- Animal Non steroidal antiinflammatory agent Dog Kinetics Species Estradiol Glucuronic acid conjugation Human In vitro Drug interaction Microsome Metabolite Estrogen Rat Pharmaceutical technology UDP-glucuronosyltransferase Carnivora Enzyme Fissipedia Glycosyltransferases Hexosyltransferases Mammalia Metabolism Pharmacokinetics Rodentia Transferases Vertebrata
- Keyword (es)
- Animal Antiinflamatorio no esteroide Perro Cinética Especie Estradiol Glucuroconjugación Hombre In vitro Interacción medicamentosa Microsoma Metabolito Estrógeno Rata Tecnología farmacéutica UDP-glucuronosyltransferase Carnivora Enzima Fissipedia Glycosyltransferases Hexosyltransferases Mammalia Metabolismo Farmacocinética Rodentia Transferases Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02A General pharmacology / 002B02A03 Pharmaceutical technology. Pharmaceutical industry
- Discipline
- General pharmacology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 20488559
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1002/jps.21185 
https://dx.doi.org/10.1002/jps.21185
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