A rapid and sensitive LC-MS/MS assay to quantify yonkenafil in rat plasma with application to preclinical pharmacokinetics studies
- Author
- JIANG WANG1 ; YAO JIANG1 ; YINGWU WANG1 ; YUNBIAO TANG2 ; GUOSHENG TENG1 ; FAWCETT, J. Paul3 ; JIAN KONG4 ; JINGKAI GU1
[1] Research Center for Drug Metabolism, College of Life Science, Jilin University, Changchun 130023, China
[2] Department of Pharmacy. General Hospital of Shenyang Military Command, Shenyang 110016, China
[3] School of Pharmacy. University of Otago. PO Box 913, Dunedin, New Zealand
[4] Internal Medicine, First Hospital, Jilin University, Changchun 130021, China - Source
Journal of pharmaceutical and biomedical analysis. 2008, Vol 47, Num 4-5, pp 985-989, 5 p ; ref : 14 ref
- CODEN
- JPBADA
- ISSN
- 0731-7085
- Scientific domain
- Medical laboratory techniques; Pharmacology drugs
- Publisher
- Elsevier Science, Amsterdam
- Publication country
- Netherlands
- Document type
- Article
- Language
- English
- Author keyword
- Yonkenafil;LC-MS/MS;Rat;Pharmacokinetics;Plasma
- Keyword (fr)
- Analyse quantitative Animal Chromatographie phase liquide Essai préclinique Liquide biologique Pharmacocinétique Plasma sanguin Rat Spectrométrie masse LC MS MS Mammalia Rodentia Vertebrata
- Keyword (en)
- Quantitative analysis Animal Liquid chromatography Preclinical trial Biological fluid Pharmacokinetics Blood plasma Rat Mass spectrometry Mammalia Rodentia Vertebrata
- Keyword (es)
- Análisis cuantitativo Animal Cromatografía fase líquida Ensayo preclínico Líquido biológico Farmacocinética Plasma sanguíneo Rata Espectrometría masa Mammalia Rodentia Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A02 Analytical, structural and metabolic biochemistry
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02A General pharmacology / 002B02A02 Analysis
- Discipline
- Analytical, structural and metabolic biochemistry General pharmacology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 20493878
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.jpba.2008.04.004 
https://dx.doi.org/10.1016/j.jpba.2008.04.004
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