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Isoquinoline derivatives isolated from the fruit of Annona muricata as 5-HTergic 5-HT1A receptor agonists in rats : Unexploited antidepressive (lead) products

Author
HASRAT, J. A1 ; DE BRUYNE, T1 ; DE BACKER, J.-P2 ; VAUQUELIN, G2 ; VLIETINCK, A1
[1] Department of Pharmaceutical Sciences, University of Antwerp, Universiteitsplein 1, 2610, Antwerp, Belgium
[2] Department of Protein Chemistry, Free University of Brussels, Paardenstraat 65, 1640, St Genesius Rode, Belgium
Source

Journal of pharmacy and pharmacology. 1997, Vol 49, Num 11, pp 1145-1149 ; ref : 17 ref

CODEN
JPPMAB
ISSN
0022-3573
Scientific domain
Pharmacology drugs
Publisher
Pharmaceutical Press, Wallingford
Publication country
United Kingdom
Document type
Article
Language
English
Keyword (fr)
Agoniste Alcaloïde Annonaceae Antidépresseur Feuille Fixation biologique Fruit In vitro Interaction moléculaire Isoquinoléine dérivé Lignée cellulaire établie Mécanisme action Médecine traditionnelle Origine humaine Origine végétale Pharmacognosie Plante médicinale Protéine recombinante Psychotrope Relation structure activité Récepteur sérotoninergique 5-HT1A Annona muricata Lignée NIH3T3 4-2 Angiospermae Dicotyledones Spermatophyta
Keyword (en)
Agonist Alkaloid Annonaceae Antidepressant agent Foil Biological fixation Fruit In vitro Molecular interaction Isoquinoline derivatives Established cell line Mechanism of action Folk medicine Human origin Plant origin Pharmacognosy Medicinal plant Recombinant protein Psychotropic Structure activity relation 5-HT1A Serotonine receptor Angiospermae Dicotyledones Spermatophyta
Keyword (es)
Agonista Alcaloide Annonaceae Antidepresor Hoja Fijación biológica Fruto In vitro Interacción molecular Isoquinoleína Línea celular establecida Mecanismo acción Medicina tradicional Origen humano Origen vegetal Farmacognosia Planta medicinal Proteína recombinante Psicotropo Relación estructura actividad Receptor serotoninérgico 5-HT1A Angiospermae Dicotyledones Spermatophyta
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02A General pharmacology / 002B02A04 Pharmacognosy. Homeopathy. Health food

Discipline
General pharmacology
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
2053131

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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