A transient cell-based phenotype assay for hepatitis C NS3/4A protease : Application to potency determinations of a novel macrocyclic inhibitor against diverse protease sequences isolated from plasma infected with HCV
- Author
- LUDMERER, Steven W1 ; GRAHAM, Donald J1 ; PATEL, Mihir1 ; GILBERT, Kevin1 ; STAHLHUT, Mark1 ; OLSEN, David B1
[1] Department of Antiviral Research, Merck Research Laboratories, P.O. Box 4, West Point, PA 19486, United States - Source
Journal of virological methods. 2008, Vol 151, Num 2, pp 301-307, 7 p ; ref : 3/4 p
- CODEN
- JVMEDH
- ISSN
- 0166-0934
- Scientific domain
- Biochemistry, molecular biology, biophysics; Biotechnology; Medical laboratory techniques; Virology
- Publisher
- Elsevier, Amsterdam
/
Elsevier, London
/
Elsevier, New York, NY
- Publication country
- Netherlands
- Document type
- Article
- Language
- English
- Author keyword
- HCV;NS3/4A;Phenotype assay;Resistance
- Keyword (fr)
- Antiviral Hépatite virale C Infection Inhibiteur protease Microbiologie Méthode Peptidases Phénotype Virologie Virus hépatite C Enzyme Flaviviridae Hepacivirus Hydrolases Virose Virus
- Keyword (en)
- Antiviral Viral hepatitis C Infection Protease inhibitor Microbiology Method Peptidases Phenotype Virology Hepatitis C virus Enzyme Flaviviridae Hepacivirus Hydrolases Viral disease Virus
- Keyword (es)
- Antiviral Hepatítis virica C Infección Inhibidor proteasa Microbiología Método Peptidases Fenotipo Virología Hepatitis C virus Enzima Flaviviridae Hepacivirus Hydrolases Virosis Virus
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A05 Microbiology / 002A05C Virology / 002A05C09 Techniques used in virology
- Discipline
- Microbiology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 20531767
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.jviromet.2008.05.014 
https://dx.doi.org/10.1016/j.jviromet.2008.05.014
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