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A robust ex vivo model for evaluation of induction of apoptosis by rhTRAIL in combination with proteasome inhibitor MG132 in human premalignant cervical explants

Author
HOUGARDY, Brigitte M. T1 ; REESINK-PETERS, Nathalie1 ; VAN DEN HEUVEL, Fiona A. J1 ; TEN HOOR, Klaske A1 ; HOLLEMA, Harry2 ; DE VRIES, Elisabeth G. E3 ; DE JONG, Steven3 ; VAN DER ZEE, Ate G. J1
[1] Department of Gynecologic Oncology, University Medical Centre Groningen, University of Groningen, Groningen, Netherlands
[2] Department of Pathology, University Medical Centre Groningen, University of Groningen, Groningen, Netherlands
[3] Department of Medical Oncology, University Medical Centre Groningen, University of Groningen, Groningen, Netherlands
Source

International journal of cancer. = Journal international du cancer. 2008, Vol 123, Num 6, pp 1457-1465, 9 p ; ref : 38 ref

CODEN
IJCNAW
ISSN
0020-7136
Scientific domain
Medical oncology
Publisher
Wiley-Liss, New York, NY
Publication country
United States
Document type
Article
Language
English
Author keyword
apoptosis cervical explants proteasome inhibitor rhTRAIL
Keyword (fr)
Activité biologique Anticancéreux Apoptose Association médicamenteuse Cancérologie Ex vivo Explant Homme Inhibiteur du protéasome Ligand TRAIL Lésion précancéreuse du col utérin Modèle Mort cellulaire Lésion précancéreuse Pathologie de l'appareil génital femelle Pathologie du col de l'utérus
Keyword (en)
Biological activity Antineoplastic agent Apoptosis Drug combination Cancerology Ex vivo Explant Human Proteasome inhibitor TNF related apoptosis inducing ligand Cervical precancerous lesion Models Cell death Premalignant lesion Female genital diseases Uterine cervix diseases
Keyword (es)
Actividad biológica Anticanceroso Apoptosis Asociación medicamentosa Cancerología Ex vivo Explante Hombre Inhibidor proteasome Ligando TRAIL Lesión precancerosa de cuello útero Modelo Muerte celular Lesión precancerosa Aparato genital hembra patología Cuello útero patología
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents / 002B02R01 General aspects

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B04 Tumors

Discipline
Pharmacological treatments Tumours
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
20543621

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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