Stability indicating validated HPLC method for quantification of levothyroxine with eight degradation peaks in the presence of excipients
- Author
- SHAH, R. B1 ; BRYANT, A1 ; COLLIER, J1 2 ; HABIB, M. J2 ; KHAN, M. A1
[1] Division of Product Quality Research, Office of Testing and Research, Office of Pharmaceutical Sciences, Center for Drug Evaluation and Research, Food and Drug Administration, United States
[2] Department of Pharmaceutical Sciences, School of Pharmacy, Howard University, United States - Source
International journal of pharmaceutics. 2008, Vol 360, Num 1-2, pp 77-82, 6 p ; ref : 1/2 p
- CODEN
- IJPHDE
- ISSN
- 0378-5173
- Scientific domain
- Pharmacology drugs
- Publisher
- Elsevier, Amsterdam
- Publication country
- Netherlands
- Document type
- Article
- Language
- English
- Author keyword
- Levothyroxine;Impurities;Degradation products;Validation;Excipients
- Keyword (fr)
- Chromatographie HPLC Dégradation Excipient Lévothyroxine sodique Stabilité Technologie pharmaceutique Hormone thyroïdienne Propriété physicochimique
- Keyword (en)
- HPLC chromatography Degradation Vehicle(excipient) Levothyroxine sodium Stability Pharmaceutical technology Thyroid hormone Physicochemical properties
- Keyword (es)
- Cromatografía HPLC Degradación Excipiente(vehiculo) Levotiroxina de sodio Estabilidad Tecnología farmacéutica Hormona tiroidea Propiedad fisicoquímica
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02A General pharmacology / 002B02A03 Pharmaceutical technology. Pharmaceutical industry
- Discipline
- General pharmacology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 20553875
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.ijpharm.2008.04.018 
https://dx.doi.org/10.1016/j.ijpharm.2008.04.018
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