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A three-dimensional pharmacophore model for dipeptidyl peptidase IV inhibitors

Author
WU, Ssu-Hui1 ; LU, I-Lin1 2 ; CHAO, Yu-Sheng1 ; WU, Su-Ying1 ; TSAI, Keng-Chang3 ; CHIANG, Yi-Kun1 ; JIAANG, Weir-Torn1 ; WU, Ssu-Hui1 ; MAHINDROO, Neeraj1 ; CHIEN, Chia-Hui1 ; LEE, Shiow-Ju1 ; XIN CHEN1
[1] Division of Biotechnology and Pharmaceutical Research, National Health Research Institutes, 35 Keyan Road, Zhunan Town, Miaoli County 350, Taiwan, Province of China
[2] Graduate Institute of Life Sciences, National Defense Medical Center, Taipei 114, Taiwan, Province of China
[3] Genomics Research Center, Academia Sinica, Taipei 115, Taiwan, Province of China
Source

European journal of medicinal chemistry. 2008, Vol 43, Num 8, pp 1603-1611, 9 p ; ref : 22 ref

CODEN
EJMCA5
ISSN
0223-5234
Scientific domain
Organic chemistry; Pharmacology drugs
Publisher
Elsevier, Oxford
Publication country
United Kingdom
Document type
Article
Language
English
Author keyword
CATALYST Diabetes Dipeptidyl peptidase IV Pharmacophore Structure-activity relationship
Keyword (fr)
Composé non peptide Dipeptidyl-peptidase IV Hypoglycémiant Inhibiteur enzyme Modèle 3 dimensions Modèle moléculaire Modélisation Prédiction Relation structure activité Antidiabétique Inhibiteur DPIV Enzyme Hydrolases Peptidases
Keyword (en)
Non peptide compound Dipeptidyl-peptidase IV Hypoglycemic agent Enzyme inhibitor Three dimensional model Molecular model Modeling Prediction Structure activity relation Enzyme Hydrolases Peptidases
Keyword (es)
Compuesto no péptido Dipeptidyl-peptidase IV Hipoglicemiante Inhibidor enzima Modelo 3 dimensiones Modelo molecular Modelización Predicción Relación estructura actividad Enzima Hydrolases Peptidases
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02N General and cellular metabolism. Vitamins

Discipline
Pharmacological treatments
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
20602909

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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