Soluble amyloid-β peptides potently disrupt hippocampal synaptic plasticity in the absence of cerebrovascular dysfunction in vivo
- Author
- HU, Neng-Wei1 2 ; SMITH, Imelda M3 ; WALSH, Dominic M3 ; ROWAN, Michael J1 2
[1] Trinity College Institute of Neuroscience, Trinity College, Dublin, Ireland
[2] Department of Pharmacology and Therapeutics, Trinity College, Dublin, Ireland
[3] Laboratory for Neurodegenerative Research, Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Dublin, Ireland - Source
Brain. 2008, Vol 131, pp 2414-2424, 11 p ; 9 ; ref : 1 p.3/4
- Publisher
- Oxford University Press, Oxford
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Author keyword
- Alzheimer's disease amyloid-β oligomers cerebral blood flow functional hyperaemia synaptic transmission
- Keyword (fr)
- Amyloïde Débit sanguin Démence d'Alzheimer Encéphale Hippocampe Pathologie du système nerveux Peptide Plasticité synaptique Transmission synaptique Trouble fonctionnel Hémodynamique Maladie dégénérative Pathologie de l'encéphale Pathologie du système nerveux central Système nerveux central
- Keyword (en)
- Amyloid Blood flow Alzheimer disease Encephalon Hippocampus Nervous system diseases Peptides Synaptic plasticity Synaptic transmission Dysfunction Hemodynamics Degenerative disease Cerebral disorder Central nervous system disease Central nervous system
- Keyword (es)
- Amiloide Flujo sanguíneo Demencia Alzheimer Encéfalo Hipocampo Sistema nervioso patología Péptido Plasticidad sináptica Transmisión sináptica Trastorno funcional Hemodinámica Enfermedad degenerativa Encéfalo patología Sistema nervosio central patología Sistema nervioso central
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B17 Neurology / 002B17G Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases
- Discipline
- Neurology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 20607827
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1093/brain/awn174 
https://dx.doi.org/10.1093/brain/awn174
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