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Spi-B inhibits human plasma cell differentiation by repressing BLIMP 1 and XBP-1 expression

Author
SCHMIDLIN, Heike1 ; DIEHL, Sean A1 ; NAGASAWA, Maho1 ; SCHEEREN, Ferenc A1 ; SCHOTTE, Remko1 ; UITTENBOGAART, Christel H2 ; SPITS, Hergen1 3 ; BLOM, Bianca1
[1] Department of Cell Biology and Histology, Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands
[2] Department of Microbiology, Immunology and Molecular Genetics, and Pediatrics, David Geffen School of Medicine at the University of California Los Angeles, United States
[3] Department of Immunology Discovery, Genentech, South San Francisco, CA, United States
Source

Blood. 2008, Vol 112, Num 5, pp 1804-1812, 9 p ; ref : 59 ref

ISSN
0006-4971
Scientific domain
Medical oncology; Hematology
Publisher
The Americain Society of Hematology, Washington, DC
Publication country
United States
Document type
Article
Language
English
Keyword (fr)
Cytodifférenciation Homme Immunité humorale Lymphocyte B Plasmocyte Réponse immune Répresseur transcription Facteur de transcription Ets Facteur de transcription SpiB Facteur de transcription XBP1 Protéine BLIMP 1
Keyword (en)
Cell differentiation Human Humoral immunity B-Lymphocyte Plasmocyte Immune response Transcription repressor Transcription factor Ets Transcription factor SpiB B lymphocyte induced maturation protein
Keyword (es)
Diferenciación celular Hombre Inmunidad humoral Linfocito B Plasmocito Respuesta inmune Represor transcripción
Classification
Pascal
002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A06 Fundamental immunology / 002A06C Immunobiology / 002A06C03 Lymphoid cells: ontogeny, maturation, markers, receptors, circulation and recirculation

Discipline
Fundamental immunology
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
20612972

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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