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A point mutation produced a class 3 aldehyde dehydrogenase with increased protective ability against the killing effect of cyclophosphamide

Author
KWOK KI HO1 ; MUKHOPADHYAY, Abhijit1 ; YI FENG LI1 ; MUKHOPADHYAY, Soma1 ; WEINER, Henry1
[1] Department of Biochemistry, Purdue University, 175 S. University Street, West Lafayette, IN 47907-2063, United States
Source

Biochemical pharmacology. 2008, Vol 76, Num 5, pp 690-696, 7 p ; ref : 44 ref

CODEN
BCPCA6
ISSN
0006-2952
Scientific domain
Biochemistry, molecular biology, biophysics; Pharmacology drugs; Physiology, morphology
Publisher
Elsevier Science, New York, NY
Publication country
United States
Document type
Article
Language
English
Author keyword
Aldehyde dehydrogenase Cyclophosphamide HeLa cell protection Benzaldehyde Aldophosphamide
Keyword (fr)
Aldehyde dehydrogenase (NAD+) Anticancéreux Cyclophosphamide Lignée HeLa Mutation ponctuelle Prévention Agent alkylant Dérivé de l'oxazaphosphinane Enzyme Moutarde à l'azote Oxidoreductases
Keyword (en)
Aldehyde dehydrogenase (NAD+) Antineoplastic agent Cyclophosphamide Hela cell line Point mutation Prevention Alkylating agent Oxazaphosphinane derivatives Enzyme Nitrogen mustard Oxidoreductases
Keyword (es)
Aldehyde dehydrogenase (NAD+) Anticanceroso Ciclofosfamida Célula HeLa Mutación puntual Prevención Agente alquilante Oxazafosfinano derivado Enzima Mostaza al nitrógeno Oxidoreductases
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments

Discipline
General pharmacology
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
20617794

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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