Correlation of O6-Methylguanine Methyltransferase (MGMT) Promoter Methylation With Clinical Outcomes in Glioblastoma and Clinical Strategies to Modulate MGMT Activity
- Author
- HEGI, Monika E; LILI LIU; HERMAN, James G; STUPP, Roger; WICK, Wolfgang; WELLER, Michael; MEHTA, Minesh P; GILBERT, Mark R
[1] Laboratory of Tumor Biology and Genetics, Department of Neurosurgery, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Switzerland
[2] National Center of Competence in Research Molecular Oncology, Lausanne, Switzerland
[3] Department of Neurology, University Hospital Zurich, Zurich, Switzerland
[4] Division of Hematology/Oncology, Case Western Reserve University, Cleveland, OH, United States
[5] Department of Oncology-Cancer Biology, Johns Hopkins University School of Medicine, Baltimore, MD, United States
[6] Department of NeuroOncology, Universitäts Klinikum Heidelberg, Heidelberg, Germany
[7] Department of Human Oncology, University of Wisconsin Medical School, Madison, Wl, United States
[8] Department of Neuro-Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, TX, United States - Source
Journal of clinical oncology. 2008, Vol 26, Num 25, pp 4189-4199, 11 p ; ref : 86 ref
- ISSN
- 0732-183X
- Scientific domain
- Medical oncology
- Publisher
- Lippincott Williams & Wilkins, Baltimore, MD
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Activité biologique Cancérologie Glioblastome Methylated-DNA-protein-cysteine S-methyltransferase Methyltransferases Méthylation Promoteur transcription Pronostic Cancer Enzyme Gliome malin Pathologie du système nerveux central Pathologie du système nerveux Transferases Tumeur maligne
- Keyword (en)
- Biological activity Cancerology Glioblastoma Methylated-DNA-protein-cysteine S-methyltransferase Methyltransferases Methylation Transcription promoter Prognosis Cancer Enzyme Malignant glioma Central nervous system disease Nervous system diseases Transferases Malignant tumor
- Keyword (es)
- Actividad biológica Cancerología Glioblastoma Methylated-DNA-protein-cysteine S-methyltransferase Methyltransferases Metilación Promotor transcripción Pronóstico Cáncer Enzima Glioma maligno Sistema nervosio central patología Sistema nervioso patología Transferases Tumor maligno
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B17 Neurology / 002B17E Tumors of the nervous system. Phacomatoses
- Discipline
- Neurology Tumours
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 20623097
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1200/JCO.2007.11.5964 
https://dx.doi.org/10.1200/JCO.2007.11.5964
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