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A structure-activity analysis of the variation in oxime efficacy against nerve agents

Author
MAXWELL, Donald M1 ; KOPLOVITZ, Irwin1 ; WOREK, Franz2 ; SWEENEY, Richard E1
[1] US Army Medical Research Institute of Chemical Defense, Research Division, Pharmacology Branch, 3100 Ricketts Point Road, Aberdeen Proving Ground, MD 21010-5400, United States
[2] Bundeswehr Institute of Pharmacology and Toxicology, Neuherbergstrasse 11, Munich, Germany
Source

Toxicology and applied pharmacology. 2008, Vol 231, Num 2, pp 157-164, 8 p ; ref : 3/4 p

CODEN
TXAPA9
ISSN
0041-008X
Scientific domain
Pharmacology drugs; Toxicology
Publisher
Elsevier, San Diego, CA
Publication country
United States
Document type
Article
Language
English
Author keyword
Organophosphorus nerve agents;Acetylcholinesterase;Oxime;Steric hindrance
Keyword (fr)
Antidote Efficacité traitement In vitro In vivo Nerf Neurotoxine Organophosphoré Oxime Relation structure activité Toxine
Keyword (en)
Antidote Treatment efficiency In vitro In vivo Nerve Neurotoxin Organophosphorus compounds Oxime Structure activity relation Toxin
Keyword (es)
Antídoto Eficacia tratamiento In vitro In vivo Nervio Neurotoxina Organofosforado Oxima Relación estructura actividad Toxina
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B03 Toxicology / 002B03L Chemical and industrial products toxicology. Toxic occupational diseases / 002B03L02 Gas, fumes

Discipline
Toxicology
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
20637561

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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