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AMTB, a TRPM8 channel blocker : evidence in rats for activity in overactive bladder and painful bladder syndrome

Author
LASHINGER, Erin S. R1 ; STEIGINGA, Matthew S2 ; HIEBLE, J. Paul1 ; LEON, Lisa A1 ; GARDNER, Scott D3 ; NAGILLA, Rakesh4 ; DAVENPORT, Elizabeth A2 ; HOFFMAN, Bryan E3 ; LAPING, Nicholas J1 ; XIN SU1
[1] Department of Urology, GlaxoSmithKline Pharmaceuticals, King of Prussia, Pennsylvania, United States
[2] Biological Reagents and Assay Development, GlaxoSmithKline Pharmaceuticals, King of Prussia, Pennsylvania, United States
[3] Discovery Technology Group, GlaxoSmithKline Pharmaceuticals, King of Prussia, Pennsylvania, United States
[4] Drug Metabolism and Pharmacokinetics, GlaxoSmithKline Pharmaceuticals, King of Prussia, Pennsylvania, United States
Source

American journal of physiology. Renal physiology. 2008, Vol 64, Num 3 ; F803-F810 ; ref : 35 ref

ISSN
1931-857X
Scientific domain
Physiology, morphology; Urology, nephrology
Publisher
American Physiological Society, Bethesda, MD
Publication country
United States
Document type
Article
Language
English
Author keyword
bladder distension rhythmic contraction visceromotor reflex
Keyword (fr)
Appareil urinaire Douleur Rat Réflexe Vessie hyperactive Mammalia Pathologie de l'appareil urinaire Pathologie de la vessie Pathologie des voies urinaires Rodentia Vertebrata
Keyword (en)
Urinary system Pain Rat Reflex Overactive bladder Mammalia Urinary system disease Bladder disease Urinary tract disease Rodentia Vertebrata
Keyword (es)
Aparato urinario Dolor Rata Reflejo Vejiga hiperactiva Mammalia Aparato urinario patología Vejiga patología Vía urinaria patología Rodentia Vertebrata
Classification
Pascal
002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A18 Vertebrates: urinary system

Discipline
Vertebrates : digestive and urinary system
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
20641308

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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