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A novel poloxamers/hyaluronic acid in situ forming hydrogel for drug delivery : Rheological, mucoadhesive and in vitro release properties

Author
MAYOL, Laura1 ; QUAGLIA, Fabiana1 ; BORZACCHIELLO, Assunta2 ; AMBROSIO, Luigi2 ; LA ROTONDA, Maria I1
[1] Department of Pharmaceutical and Toxicological Chemistry, University of Naples, Federico II, Naples, Italy
[2] Institute of Composite and Biomedical Materials, National Research Council (IMCB-CNR), Naples, Italy
Source

European journal of pharmaceutics and biopharmaceutics. 2008, Vol 70, Num 1, pp 199-206, 8 p ; ref : 31 ref

ISSN
0939-6411
Scientific domain
Pharmacology drugs
Publisher
Elsevier Science, Amsterdam
Publication country
Netherlands
Document type
Article
Language
English
Author keyword
Drug delivery Hyaluronic acid In situ forming gel Mucoadhesion Poloxamer Thermosensitive gel Viscoelastic properties
Keyword (fr)
Acide hyaluronique Bioadhésion Excipient Gel colloïdal Gélification Hydrogel In situ In vitro Libération Muqueuse Médicament Poloxamère Produit thermosensible Système bioadhésif Technologie pharmaceutique Vecteur médicament Forme libération contrôlée Forme pharmaceutique
Keyword (en)
Hyaluronic acid Bioadhesion Vehicle(excipient) Colloidal gel Gelation Hydrogel In situ In vitro Release Mucosa Drug Poloxamer Thermal labile product Bioadhesive system Pharmaceutical technology Drug carrier Controlled release form Dosage form
Keyword (es)
Hialurónico ácido Bioadhesión Excipiente(vehiculo) Gel coloidal Gelificación Hidrogel In situ In vitro Liberación Mucosa Medicamento Poloxámero Producto termosensible Sistema bioadhesivo Tecnología farmacéutica Vector medicamento Forma liberación controlada Forma farmacéutica
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02A General pharmacology / 002B02A03 Pharmaceutical technology. Pharmaceutical industry

Discipline
General pharmacology
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
20660019

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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