Increased epidermal growth factor receptor (EGFR) gene copy number is strongly associated with EGFR mutations and adenocarcinoma in non-small cell lung cancers : A chromogenic in situ hybridization study of 182 patients
- Author
- CHANG, John Wen-Cheng1 ; LIU, Hui-Ping2 ; HSU, Hui-Yu5 ; CHEN, Ying-Tsong5 ; TSAI, Shih-Feng5 ; CHEN, Yi-Rong5 ; HSI, Bae-Li5 ; HUANG, Shiu-Feng5 6 ; HSIEH, Meng-Heng3 ; FANG, Yueh-Fu3 ; HSIEH, Meng-Shu4 ; HSIEH, Jia-Juan1 ; CHIU, Yu-Ting5 ; TSAI, Hsien-Yu5 ; CHEN, Yi-Hsuan5 ; CHEN, Ya-Ting5
[1] Department of Hematology and Oncology, Chang Gung Memorial Hospital, TaoYuan, Taiwan, Province of China
[2] Department of Cardiovascular and Thoracic Surgery, Chang Gung Memorial Hospital, TaoYuan, Taiwan, Province of China
[3] Department of Thoracic Medicine, Chang Gung Memorial Hospital, TaoYuan, Taiwan, Province of China
[4] Department of Family Medicine, Chang Gung Memorial Hospital, TaoYuan, Taiwan, Province of China
[5] Division of Molecular and Genomic Medicine, National Health Research Institute, 35 Keyan Road, Zhunan, Miaoli 35053, Taiwan, Province of China
[6] Department of Pathology, Chang Gung Memorial Hospital, TaoYuan, Taiwan, Province of China - Source
Lung cancer. 2008, Vol 61, Num 3, pp 328-339, 12 p ; ref : 39 ref
- CODEN
- LUCAE5
- ISSN
- 0169-5002
- Scientific domain
- Medical oncology; Pneumology
- Publisher
- Elsevier Science, Shannon
- Publication country
- Ireland
- Document type
- Article
- Language
- English
- Author keyword
- Chromogenic in situ hybridization EGFR mutation Gene copy number Non-small cell lung cancer Tyrosine kinase inhibitor
- Keyword (fr)
- Association Cancérologie Carcinome non petite cellule bronchopulmonaire Cellule tumorale Gène Homme Hybridation moléculaire Inhibiteur de la tyrosine kinase Mutation Nombre Pathologie de l'appareil respiratoire Pneumologie Récepteur facteur croissance épiderme Biologie moléculaire Cancer Génétique Pathologie des bronches Pathologie des poumons Tumeur maligne
- Keyword (en)
- Association Cancerology non-small cell lung carcinoma Tumor cell Gene Human Molecular hybridization Tyrosine kinase inhibitor Mutation Number Respiratory disease Pneumology Epidermal growth factor receptor Molecular biology Cancer Genetics Bronchus disease Lung disease Malignant tumor
- Keyword (es)
- Asociación Cancerología Carcinoma no pequeňa célula bronchopulmonar Célula tumoral Gen Hombre Hibridación molecular Inhibidor tyrosine kinase Mutación Número Aparato respiratorio patología Neumología Receptor del factor de crecimiento epidérmico Biología molecular Cáncer Genética Bronquio patología Pulmón patología Tumor maligno
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B11 Pneumology / 002B11A Tumors of the respiratory system and mediastinum
- Discipline
- Pulmonology Tumours
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 20687762
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.lungcan.2008.01.009 
https://dx.doi.org/10.1016/j.lungcan.2008.01.009
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