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Metabolism of irinotecan and its active metabolite SN-38 by intestinal microflora in rats

Author
YAMAMOTO, Michiko1 ; KURITA, Akinobu2 ; YOKOBA, Masanori1 ; MITSUFUJI, Hisashi1 ; NISHII, Yasuto1 ; FUKUI, Tomoya1 ; MASUDA, Noriyuki1 ; ASAHARA, Takashi2 ; TAKAKURA, Akira1 ; KATONO, Ken1 ; IWASAKI, Maiko1 ; RYUGE, Shinichiro1 ; WADA, Mayuko1 ; ONODA, Sayaka1 ; YANAIHARA, Tomoko1
[1] Department of Respiratory Medicine, Kitasato University School of Medicine, 1-15-1 Kitasato, Sagamihara, Kanagawa 228-8555, Japan
[2] Yakult Central Institute for Microbial Research, 1796 Yaho, Kunitachi, Tokyo 186-8650, Japan
Source

Oncology reports. 2008, Vol 20, Num 4, pp 727-730, 4 p ; ref : 20 ref

ISSN
1021-335X
Scientific domain
Medical oncology
Publisher
[S.n.], Athens
Publication country
Greece
Document type
Article
Language
English
Author keyword
SN-38 adsorption diarrhea intestinal microorganisms irinotecan
Keyword (fr)
Adsorption Animal Anticancéreux Cancérologie Diarrhée Intestin Irinotécan Microflore Microorganisme Métabolisme Métabolite Rat Camptothécine(7-éthyl-10-hydroxy) Appareil digestif Camptothécine dérivé DNA topoisomerase Enzyme Inhibiteur de la topoisomérase I Inhibiteur enzyme Isomerases Mammalia Pathologie de l'appareil digestif Pathologie de l'intestin Rodentia Vertebrata
Keyword (en)
Adsorption Animal Antineoplastic agent Cancerology Diarrhea Gut Irinotecan Microflora Microorganism Metabolism Metabolite Rat Digestive system Camptothecin derivatives DNA topoisomerase Enzyme Topoisomerase I inhibitor Enzyme inhibitor Isomerases Mammalia Digestive diseases Intestinal disease Rodentia Vertebrata
Keyword (es)
Adsorción Animal Anticanceroso Cancerología Diarrea Intestino Irinotecán Microflora Microorganismo Metabolismo Metabolito Rata Aparato digestivo Camptothecin derivado DNA topoisomerase Enzima Inhibidor topoisomerase I Inhibidor enzima Isomerases Mammalia Aparato digestivo patología Intestino patología Rodentia Vertebrata
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B04 Tumors

Discipline
Tumours
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
20703258

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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