Effects of the Incorporation of a Hydrophobic Middle Block into a PEG-Polycation Diblock Copolymer on the Physicochemical and Cell Interaction Properties of the Polymer-DNA Complexes
- Author
- SHARMA, Rahul1 ; LEE, Jae-Sung1 ; BETTENCOURT, Ryan C2 ; CHUAN XIAO2 ; KONIECZNY, Stephen F2 ; WON, You-Yeon1
[1] School of Chemical Engineering, Purdue University, West Lafayette, Indiana 47907, United States
[2] Department of Biological Sciences, Purdue University, West Lafayette, Indiana 47907, United States - Source
Biomacromolecules. 2008, Vol 9, Num 11, pp 3294-3307, 14 p ; ref : 57 ref
- ISSN
- 1525-7797
- Scientific domain
- Biochemistry, molecular biology, biophysics; Polymers, paint and wood industries
- Publisher
- American Chemical Society, Washington, DC
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Acrylate de butyle copolymère Amine copolymère Copolymère triséquencé Cytotoxicité DNA Erythrocyte Ethylène oxyde copolymère Etude expérimentale Interaction cellulaire Interpolymère Lignée HeLa Méthacrylate copolymère Polymère amphiphile Polymère vecteur Polyélectrolyte Potentiel électrocinétique Solution aqueuse Solution micellaire Stabilité Terpolymère Thérapie génique Transfection Vecteur médicament Morphologie micellaire Méthacrylate de 2-[diméthylamino]éthyle copolymère Polyplexe Résistance enzyme Propriété biologique
- Keyword (en)
- Butyl acrylate copolymer Amine copolymer Triblock copolymer Cytotoxicity DNA Red blood cell Ethylene oxide copolymer Experimental study Cell cell interaction Interpolymer Hela cell line Methacrylate copolymer Amphiphilic polymer Control release polymer Polyelectrolyte Electrokinetic potential Aqueous solution Micellar solution Stability Terpolymer Gene therapy Transfection Drug carrier Polyplex Biological properties
- Keyword (es)
- Acrilato de butilo copolímero Amina copolímero Copolímero trisecuencia Citotoxicidad DNA Eritrocito Etileno óxido copolímero Estudio experimental Interacción celular Interpolímero Célula HeLa Metacrilato copolímero Polímero amfifilo Polímero vector Polielectrolito Potencial electrocinético Solución acuosa Solución micelar Estabilidad Terpolímero Terapia génica Transfección Vector medicamento Propiedad biológica
- Classification
- Pascal
- 001 Exact sciences and technology / 001D Applied sciences / 001D09 Physicochemistry of polymers / 001D09D Organic polymers / 001D09D04 Properties and characterization / 001D09D04G Solution and gel properties
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02A General pharmacology / 002B02A03 Pharmaceutical technology. Pharmaceutical industry
- Discipline
- General pharmacology Physical chemistry of polymers
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 20874207
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1021/bm800876v 
https://dx.doi.org/10.1021/bm800876v
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