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Simple and sensitive antimalarial drug screening in vitro and in vivo using transgenic luciferase expressing Plasmodium berghei parasites

Author
FRANKE-FAYARD, B1 ; DJOKOVIC, D2 ; DOOREN, M. W1 ; RAMESAR, J1 ; WATER, A. P3 ; FALADE, M. O4 ; KRANENDONK, M5 ; MARTINELLI, A6 ; CRAVO, P6 ; JANSE, C. J1
[1] Department of Parasitology, Centre of Infectious Diseases, Leiden University Medical Centre (LUMC), Leiden, Netherlands
[2] Vascular Unit, Instituto Gulbenkian de Ciência, Rua da Quinta Grande 6, 2780-156 Oeiras, Portugal
[3] Division of Infection and Immunity, Institute of Biomedical Life Sciences & Wellcome Centre for Molecular Parasitology, Glasgow Biomedical Research Centre, University of Glasgow, Scotland, United Kingdom
[4] Malaria Research Laboratories, Institute for Advanced Medical Research and Training, College of Medicine, University of Ibadan, Ibadan, Nigeria
[5] Department of Genetics, Faculty of Medical Sciences, Universidade Nova de Lisboa, Rua da Junqueira 96, 1349-008 Lisboa, Portugal
[6] Centro de Malária e Outras Doenças Tropicais/IHMT/UNL/ Unidade de Biologia Molecular, Lisbon, Portugal
Source

International journal for parasitology. 2008, Vol 38, Num 14, pp 1651-1662, 12 p ; ref : 1/2 p

CODEN
IJPYBT
ISSN
0020-7519
Scientific domain
Tropical medicine; Parasitology; Zoology
Publisher
Elsevier, Kidlington
Publication country
United Kingdom
Document type
Article
Language
English
Author keyword
Assay Drug screening In vitro In vivo Luciferase Plasmodium berghei
Keyword (fr)
Antipaludique In vitro In vivo Médicament Parasite Plasmodium berghei Apicomplexa Protozoa
Keyword (en)
Antimalarial In vitro In vivo Drug Parasite Plasmodium berghei Apicomplexa Protozoa
Keyword (es)
Antipalúdico In vitro In vivo Medicamento Parásito Plasmodium berghei Apicomplexa Protozoa
Classification
Pascal
002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A11 Protozoa / 002A11D Life cycle. Host-agent relationship. Pathogenesis

Discipline
Protozoa
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
20889082

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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