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Pleuromutilin derivatives having a purine ring. Part 3: Synthesis and antibacterial activity of novel compounds possessing a piperazine ring spacer

Author
HIROKAWA, Yoshimi1 ; KINOSHITA, Hironori1 ; TANAKA, Tomoyuki1 ; NAKAMURA, Takanori1 ; FUJIMOTO, Koichi2 ; KASHIMOTO, Shigeki2 ; KOJIMA, Tsuyoshi2 ; KATO, Shiro1
[1] Chemistry Research Laboratories, Dainippon Sumitomo Pharma Co., Ltd, Enoki 33-94, Suita 564-0053, Japan
[2] Pharmacology Research Laboratories, Dainippon Sumitomo Pharma Co., Ltd, 3-1-98 Kasugade Naka, Konohana-ku, Osaka 554-0022, Japan
Source

Bioorganic & medicinal chemistry letters (Print). 2009, Vol 19, Num 1, pp 175-179, 5 p ; ref : 17 ref

ISSN
0960-894X
Scientific domain
Biochemistry, molecular biology, biophysics; Pharmacology drugs
Publisher
Elsevier, Amsterdam
Publication country
Netherlands
Document type
Article
Language
English
Author keyword
Gram-positive bacteria MIC MRSA PRSP Piperazine ring Pleuromutilin Purine ring Spacer VRE
Keyword (fr)
Animal Antibactérien Bactérie Gram positif Diterpène Dérivé de la pipérazine Dérivé de la purine In vitro In vivo Moraxella catarrhalis Méticilline Pénicilline Relation structure activité Résistance Souris Staphylococcus aureus Streptococcus pneumoniae Streptococcus pyogenes Synthèse chimique Terpénoïde Vancomycine 3a,9-Propanocyclopentacycloctène dérivé Bras espaceur Pleuromutiline Souche résistante méticilline Souche résistante pénicilline Souche résistante vancomycine Bactérie Mammalia Micrococcaceae Micrococcales Rodentia Streptococcaceae Vertebrata
Keyword (en)
Animal Antibacterial agent Gram positive bacteria Diterpene Piperazine derivatives Purine derivatives In vitro In vivo Moraxella catarrhalis Meticillin Penicillin Structure activity relation Resistance Mouse Staphylococcus aureus Streptococcus pneumoniae Streptococcus pyogenes Chemical synthesis Terpenoid Vancomycin Spacer arm Bacteria Mammalia Micrococcaceae Micrococcales Rodentia Streptococcaceae Vertebrata
Keyword (es)
Animal Antibacteriano Bacteria Gram positiva Diterpeno Piperazina derivado Purina derivado In vitro In vivo Moraxella catarrhalis Meticilina Penicilina Relación estructura actividad Resistencia Ratón Staphylococcus aureus Streptococcus pneumoniae Streptococcus pyogenes Síntesis química Terpenoide Vancomicina Bacteria Mammalia Micrococcaceae Micrococcales Rodentia Streptococcaceae Vertebrata
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02S Antibiotics. Antiinfectious agents. Antiparasitic agents / 002B02S02 Antibacterial agents

Discipline
Pharmacological treatments
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
21030116

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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