Epidermal growth factor receptor status and persistent activation of Akt and p44/42 MAPK pathways correlate with the effect of cetuximab in head and neck and colon cancer cell lines
- Author
- YAMATODANI, Takashi1 2 ; EKBLAD, Lars3 ; KJELLEN, Elisabeth3 ; JOHNSSON, Anders3 ; MINETA, Hiroyuki2 ; WENNERBERG, Johan1
[1] Department of Otorhinolaryngology/Head and Neck Surgery, Lund University Hospital, 221 85 Lund, Sweden
[2] Department of Otorhinolaryngology/Head and Neck Surgery, Hamamatsu University School of Medicine, Hamamatsu 431-3192, Japan
[3] Department of Oncology, Lund University Hospital, 221 85 Lund, Sweden - Source
Journal of cancer research and clinical oncology. 2009, Vol 135, Num 3, pp 395-402, 8 p ; ref : 1 p
- CODEN
- JCROD7
- ISSN
- 0171-5216
- Scientific domain
- Medical oncology; Pharmacology drugs
- Publisher
- Springer, Heidelberg
- Publication country
- Germany
- Document type
- Article
- Language
- English
- Author keyword
- Cetuximab Colon cancer EGFR Head and neck cancer Signalling pathways
- Keyword (fr)
- Activation Akt protein kinase Anticancéreux Cancer de la tête et du cou Cancer du côlon Cellule tumorale Cétuximab In vitro Lignée cellulaire établie Mitogen-activated protein kinase Récepteur facteur croissance épiderme Récepteur facteur croissance Transduction signal Tête cou Anti-EGFR Voie de signalisation Anticorps monoclonal Cancer Enzyme Pathologie ORL Pathologie de l'appareil digestif Pathologie de l'intestin Pathologie du côlon Régulation Transferases Tumeur maligne
- Keyword (en)
- Activation Akt protein kinase Antineoplastic agent Head and neck cancer Colon cancer Tumor cell Cetuximab In vitro Established cell line Mitogen-activated protein kinase Epidermal growth factor receptor Growth factor receptor Signal transduction Head and neck Signaling pathway Monoclonal antibody Cancer Enzyme ENT disease Digestive diseases Intestinal disease Colonic disease Regulation(control) Transferases Malignant tumor
- Keyword (es)
- Activación Akt protein kinase Anticanceroso Cáncer de cabeza y cuello Cáncer del colon Célula tumoral Cetuximab In vitro Línea celular establecida Mitogen-activated protein kinase Receptor del factor de crecimiento epidérmico Receptor factor crecimiento Transducción señal Cabeza cuello Anticuerpo monoclonal Cáncer Enzima ORL patología Aparato digestivo patología Intestino patología Colón patología Regulación Transferases Tumor maligno
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B10 Otorhinolaryngology. Stomatology / 002B10A Otorhinolaryngology (head neck, general aspects and miscellaneous) / 002B10A01 Tumors
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B13 Gastroenterology. Liver. Pancreas. Abdomen / 002B13B Stomach. Duodenum. Small intestine. Colon. Rectum. Anus / 002B13B01 Tumors
- Discipline
- Gastroenterology. Liver. Pancreas. Abdomen Otorhinolaryngology. Stomatology Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 21100713
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1007/s00432-008-0475-2 
https://dx.doi.org/10.1007/s00432-008-0475-2
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