Epithelial to mesenchymal transition derived from repeated exposure to gefitinib determines the sensitivity to EGFR inhibitors in A549, a non-small cell lung cancer cell line
- Author
- JIN KYUNG RHO1 ; CHOI, Yunjung1 ; JIN KYUNG LEE2 ; RYOO, Baek-Yeol1 ; IM IL NA1 ; SUNG HYUN YANG1 ; CHEOL HYEON KIM1 ; JAE CHEOL LEE1
[1] Department of Internal Medicine, Korea Cancer Center Hospital, Korea Institute of Radiological & Medical Science, 215-4 Gongneung-dong, Nowon-gu, Seoul 139-706, Korea, Republic of
[2] Department of Laboratory Medicine, Korea Cancer Center Hospital, Korea Institute of Radiological & Medical Science, 215-4 Gongneung-dong, Nowon-gu, Seoul 139-706, Korea, Republic of - Source
Lung cancer. 2009, Vol 63, Num 2, pp 219-226, 8 p ; ref : 47 ref
- CODEN
- LUCAE5
- ISSN
- 0169-5002
- Scientific domain
- Medical oncology; Pneumology
- Publisher
- Elsevier, Oxford
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Author keyword
- EGFR EMT Gefitinib Lung cancer Resistance TGF-β1
- Keyword (fr)
- Cancer du poumon Cancérologie Carcinome non petite cellule bronchopulmonaire Exposition Facteur croissance transformant β1 Géfitinib Inhibiteur Lignée cellulaire Mésenchyme Pathologie de l'appareil respiratoire Pneumologie Récepteur facteur croissance épiderme Résistance Sensibilité Transition Cancer Pathologie des bronches Pathologie des poumons Tumeur maligne
- Keyword (en)
- Lung cancer Cancerology non-small cell lung carcinoma Exposure Transforming growth factor β1 Gefitinib Inhibitor Cell line Mesenchyma Respiratory disease Pneumology Epidermal growth factor receptor Resistance Sensitivity Transition Cancer Bronchus disease Lung disease Malignant tumor
- Keyword (es)
- Cáncer del pulmón Cancerología Carcinoma no pequeňa célula bronchopulmonar Exposición Factor crecimiento transformante β1 Gefitinib Inhibidor Línea celular Mesénquima Aparato respiratorio patología Neumología Receptor del factor de crecimiento epidérmico Resistencia Sensibilidad Transición Cáncer Bronquio patología Pulmón patología Tumor maligno
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B11 Pneumology / 002B11A Tumors of the respiratory system and mediastinum
- Discipline
- Pulmonology Tumours
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 21123087
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.lungcan.2008.05.017 
https://dx.doi.org/10.1016/j.lungcan.2008.05.017
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