DNA binding, cytotoxicity, apoptotic inducing activity, and molecular modeling study of quercetin zinc(II) complex
- Author
- JUN TAN1 2 3 ; BOCHU WANG1 ; LIANCAI ZHU1
[1] Bioengineering College, Chongqing University, Chongqing 400030, China
[2] Department of Life Science and Chemistry, Chongqing Education College, Chongqing 400067, China
[3] Post-doctoral Research Center of Mechanics, Mechanical Resource and Environment College, Chongqing University, Chongqing 400030, China - Source
Bioorganic & medicinal chemistry. 2009, Vol 17, Num 2, pp 614-620, 7 p ; ref : 36 ref
- ISSN
- 0968-0896
- Scientific domain
- Biochemistry, molecular biology, biophysics; Pharmacology drugs
- Publisher
- Elsevier, Amsterdam
- Publication country
- Netherlands
- Document type
- Article
- Language
- English
- Author keyword
- Antitumor activity DNA binding Intercalation Quercetin zinc(II) complex
- Keyword (fr)
- Activité biologique Anticancéreux Apoptose Carcinome hépatocellulaire Cellule tumorale Complexe aqua Cytotoxicité DNA Dérivé de la flavone Fixation biologique Flavonoïde Foie Homme Hépatocyte In vitro Lignée cellulaire Modèle moléculaire Modélisation Polyphénol Quercétine Zinc II Complexe Fixation DNA Lignée HEPG2 Lignée SMMC7721 Métal divalent Complexe Métal transition Complexe
- Keyword (en)
- Biological activity Antineoplastic agent Apoptosis Hepatocellular carcinoma Tumor cell Aqua complex Cytotoxicity DNA Flavone derivatives Biological fixation Flavonoid Liver Human Hepatocyte In vitro Cell line Molecular model Modeling Polyphenol Quercetin Zinc II Complexes Divalent metal Complexes Transition metal Complexes
- Keyword (es)
- Actividad biológica Anticanceroso Apoptosis Carcinoma hepatocelular Célula tumoral Complejo aqua Citotoxicidad DNA Flavona derivado Fijación biológica Flavonoide Hígado Hombre Hepatocito In vitro Línea celular Modelo molecular Modelización Polifenol Quercetina Zinc II Complejo Metal divalente Complejo Metal transición Complejo
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents / 002B02R01 General aspects
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 21127098
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.bmc.2008.11.063 
https://dx.doi.org/10.1016/j.bmc.2008.11.063
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