Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction

Author

GUDBJARTSSON, Daniel F¹ ; BJORNSDOTTIR, Unnur S^{1 2} ; WILLIAMS, Carolyn^{3 4 5} ; HUI, Jennie^{6 7} ; BEILBY, John^{6 8} ; WARRINGTON, Nicole M⁹ ; JAMES, Alan^{10 11} ; PALMER, Lyle J⁹ ; KOPPELMAN, Gerard H¹² ; HEINZMANN, Andrea¹³ ; KRUEGER, Marcus¹³ ; MARIKE BOEZEN, H¹⁴ ; HALAPI, Eva¹ ; WHEATLEY, Amanda¹⁵ ; ALTMULLER, Janine¹⁶ ; HYOUNG DOO SHIN^{17 18} ; UH, Soo-Taek¹⁹ ; HYUN SUB CHEONG¹⁹ ; JONSDOTTIR, Brynja²⁰ ; GISLASON, David²⁰ ; PARK, Choon-Sik²¹ ; RASMUSSEN, Linda M²² ; PORSBJERG, Celeste²² ; HELGADOTTIR, Anna¹ ; HANSEN, Jakob W²² ; BACKER, Vibeke²² ; WERGE, Thomas²³ ; JANSON, Christer²⁴ ; JÖNSSON, Ulla-Britt²⁴ ; NG, Maggie C. Y²⁵ ; JULIANA CHAN²⁵ ; WING YEE SO²⁵ ; MA, Ronald²⁵ ; SHAH, Svati H; SULEM, Patrick¹ ; GRANGER, Christopher B; QUYYUMI, Arshed A; LEVEY, Allan I; VACCARINO, Viola; REILLY, Muredach P; RADER, Daniel J ; WILLIAMS, Michael J. A; VAN RIJ, Andre M; JONES, Gregory T; TRABETTI, Elisabetta; JONSDOTTIR, Gudrun M¹ ; MALERBA, Giovanni; PIGNATTI, Pier Franco; BONER, Attilio; PESCOLLDERUNGG, Lydia; GIRELLI, Domenico; OLIVIERI, Oliviero; MARTINELLI, Nicola; LUDVIKSSON, Bjorn R^{2 20} ; LUDVIKSDOTTIR, Dora²⁰ ; EYJOLFSSON, Gudmundur I; THORLEIFSSON, Gudmar¹ ; HELGADOTTIR, Hafdis¹ ; STEINTHORSDOTTIR, Valgerdur¹ ; STEFANSSON, Hreinn¹
[1] deCODE Genetics, Sturlugata 8, 101 Reykjavik, Iceland
[2] Faculty of Medicine, University of Iceland, 101 Reykjavik, Iceland
[3] The Lung Institute of Western Australia, Nedlands WA 6006, Australia
[4] The Western Australian Institute of Medical Research, Perth WA 6000, Australia
[5] The Centre for Asthma, Allergy and Respiratory Research, University of Western Australia, Perth WA 6009, Australia
[6] Department of Molecular Genetics, PathWest Laboratory Medicine of Western Australia, QEII Medical Centre, Nedlands WA 6009, Australia
[7] Western Australian Institute for Medical Research, B Block, QEII Medical Centre, The University of Western Australia, Nedlands WA 6009, Australia
[8] School of Surgery and Pathology, University of Western Australia, Perth WA 6009, Australia
[9] Centre for Genetic Epidemiology and Biostatistics, University of Western Australia, Perth WA 6009, Australia
[10] West Australian Sleep Disorders Research Institute, Department of Pulmonary Physiology, Sir Charles Gairdner Hospital, Nedlands WA 6009, Australia
[11] School of Medicine and Pharmacology, The University of Western Australia, Nedlands WA 6009, Australia
[12] Department of Pediatric Pulmonology and Pediatric Allergology, Beatrix Children's Hospital, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, Netherlands
[13] Centre of Pediatrics and Adolescent Medicine, University of Freiburg, 79085 Freiburg, Germany
[14] Department of Epidemiology, University Medical Center, University of Groningen, 9700 RB Groningen, Netherlands
[15] Division of Therapeutics, University Hospital of Nottingham, Queen's Medical Centre, Nottingham NG7 2UH, United Kingdom
[16] Cologne Center for Genomics, University of Cologne, 50923 Cologne, Germany
[17] Laboratory of Genomic Diversity, Department of Life Science, Sogang University, Seoull21-742, Korea, Republic of
[18] Department of Genetic Epidemiology, SNP Genetics, Inc, Seoul 153-803, Korea, Republic of
[19] Division of Allergy and Respiratory Medicine, Soonchunhyang University Seoul Hospital, 140-210 Seoul, Korea, Republic of
[20] Landspitali University Hospital, 101 Reykjavik, Iceland
[21] Division of Allergy and Respiratory Medicine, Soonchunhyang University, Bucheon Hospital, 420-031 Puchon, Korea, Republic of
[22] Department of Respitory Medicine, Bispebjerg Hospital, Copenhagen University Hospital, 2400 Copenhagen, Denmark
[23] Research Institute of Biological Psychiatry, Sct. Hans Hospital, Boserupvej 2, 4000 Roskilde, Denmark
[24] Department of Medical Sciences: Inflammation, Uppsala University, 75105 Uppsala, Sweden
[25] Department of Medicine and Therapeutics, Prince of Wales Hospital, Chinese University of Hong Kong, Shatin, Hong-Kong

Source

Nature genetics. 2009, Vol 41, Num 3, pp 342-347, 6 p ; ref : 28 ref

CODEN

NGENEC

ISSN

1061-4036

Scientific domain

Genetics

Publisher

Nature Publishing Group, New York, NY

Publication country

United States

Document type

Article

Language

English

Keyword (fr)

Asthme Infarctus du myocarde Variant Bronchopneumopathie obstructive Cardiopathie coronaire Pathologie de l'appareil circulatoire Pathologie de l'appareil respiratoire Pathologie des bronches Pathologie des poumons Pathologie du myocarde

Keyword (en)

Asthma Myocardial infarction Variant Obstructive pulmonary disease Coronary heart disease Cardiovascular disease Respiratory disease Bronchus disease Lung disease Myocardial disease

Keyword (es)

Asma Infarto miocardio Variante Enfermedad pulmonar obstructiva Cardiopatía coronaria Aparato circulatorio patología Aparato respiratorio patología Bronquio patología Pulmón patología Miocardio patología

Classification

Pascal

002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A07 Genetics of eukaryotes. Biological and molecular evolution

Pascal

002 Biological and medical sciences / 002B Medical sciences / 002B11 Pneumology / 002B11B Chronic obstructive pulmonary disease, asthma

Pascal

002 Biological and medical sciences / 002B Medical sciences / 002B12 Cardiology. Vascular system / 002B12A Heart / 002B12A03 Coronary heart disease

Discipline

Cardiology. Circulatory system Eukaryotes genetics. Biological and molecular evolution Pulmonology

Origin

Inist-CNRS

Database

PASCAL

INIST identifier

21176945

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS