MiR-1 Overexpression Enhances Ca2+ Release and Promotes Cardiac Arrhythmogenesis by Targeting PP2A Regulatory Subunit B56a and Causing CaMKII-Dependent Hyperphosphorylation of RyR2
- Author
- TERENTYEV, Dmitry1 ; BELEVYCH, Andriy E1 ; TERENTYEVA, Radmila1 ; MARTIN, Mickey M1 ; MALANA, Geraldine E1 ; KUHN, Donald E1 ; ABDELLATIF, Maha2 ; FELDMAN, David S1 ; ELTON, Terry S1 ; GYÖRKE, Sandor1
[1] Davis Heart and Lung Research Institute Ohio State University, Columbus, United States
[2] Cardiovascular Research Institute Department of Cell Biology and Molecular Medicine, University of Medicine and Dentistry of New Jersey, Newark, United States - Source
Circulation research. 2009, Vol 104, Num 4, pp 514-521, 8 p ; ref : 38 ref
- CODEN
- CIRUAL
- ISSN
- 0009-7330
- Scientific domain
- Cardiology, blood circulation, phlebology
- Publisher
- Lippincott Williams & Wilkins, Hagerstown, MD
- Publication country
- United States
- Document type
- Article
- Language
- English
- Author keyword
- CaMKII PP2A arrhythmia miR-1 ryanodine receptor
- Keyword (fr)
- Appareil circulatoire Ca2+/calmodulin-dependent protein kinase Calcium Ciblage Libération Mammalia Récepteur ryanodine Sousunité Surexpression génique Trouble du rythme cardiaque Cardiopathie Elément minéral Enzyme Pathologie de l'appareil circulatoire Transferases Vertebrata
- Keyword (en)
- Circulatory system Ca2+/calmodulin-dependent protein kinase Calcium Targeting Release Mammalia Ryanodine receptor Subunit Gene overexpression Arrhythmia Heart disease Inorganic element Enzyme Cardiovascular disease Transferases Vertebrata
- Keyword (es)
- Aparato circulatorio Ca2+/calmodulin-dependent protein kinase Calcio Blancado Liberación Mammalia Receptor ryanodina Subunitad Sobreexpresión genética Arritmia Cardiopatía Elemento inorgánico Enzima Aparato circulatorio patología Transferases Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A22 Vertebrates: cardiovascular system
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B12 Cardiology. Vascular system / 002B12A Heart / 002B12A02 Cardiac dysrhythmias
- Discipline
- Cardiology. Circulatory system Vertebrates : cardiovascular system
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 21205790
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1161/CIRCRESAHA.108.181651 
https://dx.doi.org/10.1161/CIRCRESAHA.108.181651
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