Polyamidoamine Dendrimers with a Modified Pentaerythritol Core Having High Efficiency and Low Cytotoxicity as Gene Carriers
- Author
- YANMING WANG1 2 ; WEILING KONG1 ; YU SONG1 ; YAJUN DUAN1 ; LIANYONG WANG1 ; STEINHOFF, Gustav3 ; DELING KONG1 ; YAOTING YU1
[1] Key Laboratory of Bioactive Materials, Ministry of Education, College of Life Science, Nankai University, Tianjin 300071, China
[2] College of Pharmacy, Nankai University, Tianjin 300071, China
[3] Department of Cardiac Surgery, University of Rostock, Rostock, Germany - Source
Biomacromolecules. 2009, Vol 10, Num 3, pp 617-622, 6 p
- ISSN
- 1525-7797
- Scientific domain
- Biochemistry, molecular biology, biophysics; Polymers, paint and wood industries
- Publisher
- American Chemical Society, Washington, DC
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Amidoamine polymère Cytotoxicité DNA Dendrimère Dimension particule Etude expérimentale Fibroblaste In vitro Polymère aliphatique Polymère ramifié Polymère vecteur Potentiel électrocinétique Pouvoir tampon Préparation Solution aqueuse Stabilité Thérapie génique Transfection Vecteur médicament pK Méthode divergente Polyplexe Polymère aromatique Propriété biologique
- Keyword (en)
- Amidoamine polymer Cytotoxicity DNA Dendrimer Particle size Experimental study Fibroblast In vitro Aliphatic polymer Branched polymer Control release polymer Electrokinetic potential Buffering capacity Preparation Aqueous solution Stability Gene therapy Transfection Drug carrier pK Aromatic polymer Biological properties
- Keyword (es)
- Amidoamina polímero Citotoxicidad DNA Dendrímero Dimensión partícula Estudio experimental Fibroblasto In vitro Polímero alifático Polímero ramificado Polímero vector Potencial electrocinético Poder tampón Preparación Solución acuosa Estabilidad Terapia génica Transfección Vector medicamento pK Polímero aromático Propiedad biológica
- Classification
- Pascal
- 001 Exact sciences and technology / 001D Applied sciences / 001D09 Physicochemistry of polymers / 001D09D Organic polymers / 001D09D02 Preparation, kinetics, thermodynamics, mechanism and catalysts / 001D09D02E Polymers with particular properties
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02A General pharmacology / 002B02A03 Pharmaceutical technology. Pharmaceutical industry
- Discipline
- General pharmacology Physical chemistry of polymers
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 21243169
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1021/bm801333s 
https://dx.doi.org/10.1021/bm801333s
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