Beta-catenin status in paediatric medulloblastomas : correlation of immunohistochemical expression with mutational status, genetic profiles, and clinical characteristics
- Author
- FATTET, Sarah1 2 3 ; HABERLER, Christine1 2 4 ; BARILLOT, Emmanuel10 2 9 ; GRILL, Jacques11 ; DOZ, Francois13 7 ; PUGET, Stephanie14 ; JANOUEIX-LEROSEY, Isabelle1 2 ; DELATTRE, Olivier1 2 ; LEGOIX, Patricia5 ; VARLET, Pascale6 ; LELLOUCH-TUBIANA, Arielle7 8 ; LAIR, Severine10 2 9 ; MANE, Elodie1 2 ; RAQUIN, Marie-Anne11 ; SOURS, Danielle12 ; CARPENTER, Sabrina10 2 9
[1] INSERM U830, Laboratoire de Génétique et Biologie des Cancers, 75248 Pans, France
[2] Institut Curie, Centre de Recherche, 26 Rue d'Ulm, 75248 Paris, France
[3] Centre Hospitalier Universitaire Vaudois, Hématologie et Oncologie Pédiatrique, 101 1 Lausanne, Switzerland
[4] Institute of Neurology, Médical University of Vienna, Waehringer Guertel 18-20, 1097 Vienna, Austria
[5] Institut Curie, Département de Transfert, 26 Rue d'Ulm, 75248 Paris, France
[6] Centre Hospitalier Sainte Anne, Laboratoire de Neuropathologie, 1 Rue Cabanis, 75014 Paris, France
[7] Université Paris Descartes, Faculté de Médecine, 12 Rue de l'Ecole de Médecine, 75006 Paris, France
[8] Hôpital Necker Enfants Malades, Anatomie Pathologique, 149 Rue de Sèvres, 75015 Paris, France
[9] INSERM U900, Bioinformatique, 75248 Pans, France
[10] Ecole des Mines ParisTech, 77300 Fontainebleau, France
[11] Institut Gustave-Roussy, Oncologie Pédiatrique, 39 Rue Camille Desmoulins, 94805 Villejuif, France
[12] Institut Curie, Biostatistiques, 75248 Paris, France
[13] Institut Curie, Oncologie Pédiatrique, 26 Rue d'Ulm, 75005 Paris, France
[14] Hôpital Necker Enfants Malades, Neurochirurgie Pédiatrique, 149 Rue de Sèvres, 75015 Paris, France - Source
Journal of pathology (Print). 2009, Vol 218, Num 1, pp 86-94, 9 p ; ref : 35 ref
- CODEN
- JPTLAS
- ISSN
- 0022-3417
- Scientific domain
- Medical oncology; Medical laboratory techniques; General medicine general surgery
- Publisher
- Wiley, Chichester
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Author keyword
- CTNNB1 mutation array CGH chromosome 6 deletion expression profile immunocytochemistry medulloblastoma neoplasia survival β-catenin
- Keyword (fr)
- Anatomopathologie Beta Caténine β Chromosome 6 Corrélation Délétion Enfant Expression génique Génétique Hybridation génomique comparative Immunocytochimie Immunohistochimie Mutation Médulloblastome Survie Symptomatologie Tumeur maligne Angiospermae Cancer Chenopodiaceae Dicotyledones Homme Pathologie de l'encéphale Pathologie du système nerveux central Pathologie du système nerveux Spermatophyta
- Keyword (en)
- Anatomic pathology Beta β Catenin Chromosome 6 Correlation Deletion Child Gene expression Genetics Comparative genomic hybridization Immunocytochemistry Immunohistochemistry Mutation Medulloblastoma Survival Symptomatology Malignant tumor Angiospermae Cancer Chenopodiaceae Dicotyledones Human Cerebral disorder Central nervous system disease Nervous system diseases Spermatophyta
- Keyword (es)
- Anatomía patológica Beta Catenina β Cromosoma 6 Correlación Deleción Niño Expresión genética Genética Hibridación genómica comparativa Inmunocitoquímica Inmunohistoquímica Mutación Meduloblastoma Sobrevivencia Sintomatología Tumor maligno Angiospermae Cáncer Chenopodiaceae Dicotyledones Hombre Encéfalo patología Sistema nervosio central patología Sistema nervioso patología Spermatophyta
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B17 Neurology / 002B17E Tumors of the nervous system. Phacomatoses
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B24 Investigative techniques, diagnostic techniques (general aspects) / 002B24O Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques
- Discipline
- Neurology Scanning and diagnostic techniques
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 21304600
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1002/path.2514 
https://dx.doi.org/10.1002/path.2514
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