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Polymer-Modified Gadolinium Metal-Organic Framework Nanoparticles Used as Multifunctional Nanomedicines for the Targeted Imaging and Treatment of Cancer

Author
ROWE, Misty D1 ; THAMM, Douglas H2 ; KRAFT, Susan L2 ; BOYES, Stephen G1
[1] Department of Chemistry and Geochemistry, Colorado School of Mines, Golden, Colorado 80401, United States
[2] College of Veterinary Medicine and Biological Sciences, Animal Cancer Center, Colorado State University, Fort Collins, Colorado 80526, United States
Source

Biomacromolecules. 2009, Vol 10, Num 4, pp 983-993, 11 p

ISSN
1525-7797
Scientific domain
Biochemistry, molecular biology, biophysics; Polymers, paint and wood industries
Publisher
American Chemical Society, Washington, DC
Publication country
United States
Document type
Article
Language
English
Keyword (fr)
Acrylamide dérivé copolymère Activité biologique Agent contraste paramagnétique Anticancéreux Cellule endothéliale Cellule tumorale Ciblage Composé du gadolinium Copolymère marqué Copolymérisation radicalaire Copulation chimique Etude expérimentale Groupe latéral Imagerie RMN biomédicale In vitro Marqueur fluorescent Modification chimique Méthacrylate copolymère Méthotrexate Nanoparticule Peptide Polymère greffé Polymère vecteur Préparation Réaction surface Sarcome Stabilité chimique Théranostique Transfert chaîne Trithiocarbonate organique Vecteur médicament Acrylamide(N-isopropyl) copolymère Acrylate de succinimidyle copolymère Addition fragmentation réversible Agent ciblage
Keyword (en)
Acrylamide derivative copolymer Biological activity Paramagnetic contrast agent Antineoplastic agent Endothelial cell Tumor cell Targeting Gadolinium compound Labelled copolymer Radical copolymerization Chemical coupling Experimental study Lateral group Biomedical MRI In vitro Fluorescent tracer Chemical modification Methacrylate copolymer Methotrexate Nanoparticle Peptides Graft polymers Control release polymer Preparation Surface reaction Sarcoma Chemical stability Theranostics Chain transfer Organic trithiocarbonate Drug carrier
Keyword (es)
Acrilamida derivado copolímero Actividad biológica Agente contraste paramagnético Anticanceroso Célula endotelial Célula tumoral Blancado Gadolinio compuesto Copolímero marcado Copolimerización radical Copulación química Estudio experimental Grupo lateral In vitro Marcador fluorescente Modificación química Metacrilato copolímero Metotrexato Nanopartícula Péptido Polímero vector Preparación Reacción superficie Sarcoma Estabilidad química Theranostic Transferencia en cadena Tritiocarbonato orgánico Vector medicamento
Classification
Pascal
001 Exact sciences and technology / 001D Applied sciences / 001D10 Polymer industry, paints, wood / 001D10A Technology of polymers / 001D10A06 Forms of application and semi-finished materials / 001D10A06K Miscellaneous

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02A General pharmacology / 002B02A03 Pharmaceutical technology. Pharmaceutical industry

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B24 Investigative techniques, diagnostic techniques (general aspects) / 002B24A Radiodiagnosis. Nmr imagery. Nmr spectrometry / 002B24A10 Miscellaneous. Technology

Discipline
General pharmacology Polymer industry, paints, wood Scanning and diagnostic techniques
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
21377961

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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