Polymer-Modified Gadolinium Metal-Organic Framework Nanoparticles Used as Multifunctional Nanomedicines for the Targeted Imaging and Treatment of Cancer
- Author
- ROWE, Misty D1 ; THAMM, Douglas H2 ; KRAFT, Susan L2 ; BOYES, Stephen G1
[1] Department of Chemistry and Geochemistry, Colorado School of Mines, Golden, Colorado 80401, United States
[2] College of Veterinary Medicine and Biological Sciences, Animal Cancer Center, Colorado State University, Fort Collins, Colorado 80526, United States - Source
Biomacromolecules. 2009, Vol 10, Num 4, pp 983-993, 11 p
- ISSN
- 1525-7797
- Scientific domain
- Biochemistry, molecular biology, biophysics; Polymers, paint and wood industries
- Publisher
- American Chemical Society, Washington, DC
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Acrylamide dérivé copolymère Activité biologique Agent contraste paramagnétique Anticancéreux Cellule endothéliale Cellule tumorale Ciblage Composé du gadolinium Copolymère marqué Copolymérisation radicalaire Copulation chimique Etude expérimentale Groupe latéral Imagerie RMN biomédicale In vitro Marqueur fluorescent Modification chimique Méthacrylate copolymère Méthotrexate Nanoparticule Peptide Polymère greffé Polymère vecteur Préparation Réaction surface Sarcome Stabilité chimique Théranostique Transfert chaîne Trithiocarbonate organique Vecteur médicament Acrylamide(N-isopropyl) copolymère Acrylate de succinimidyle copolymère Addition fragmentation réversible Agent ciblage
- Keyword (en)
- Acrylamide derivative copolymer Biological activity Paramagnetic contrast agent Antineoplastic agent Endothelial cell Tumor cell Targeting Gadolinium compound Labelled copolymer Radical copolymerization Chemical coupling Experimental study Lateral group Biomedical MRI In vitro Fluorescent tracer Chemical modification Methacrylate copolymer Methotrexate Nanoparticle Peptides Graft polymers Control release polymer Preparation Surface reaction Sarcoma Chemical stability Theranostics Chain transfer Organic trithiocarbonate Drug carrier
- Keyword (es)
- Acrilamida derivado copolímero Actividad biológica Agente contraste paramagnético Anticanceroso Célula endotelial Célula tumoral Blancado Gadolinio compuesto Copolímero marcado Copolimerización radical Copulación química Estudio experimental Grupo lateral In vitro Marcador fluorescente Modificación química Metacrilato copolímero Metotrexato Nanopartícula Péptido Polímero vector Preparación Reacción superficie Sarcoma Estabilidad química Theranostic Transferencia en cadena Tritiocarbonato orgánico Vector medicamento
- Classification
- Pascal
- 001 Exact sciences and technology / 001D Applied sciences / 001D10 Polymer industry, paints, wood / 001D10A Technology of polymers / 001D10A06 Forms of application and semi-finished materials / 001D10A06K Miscellaneous
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02A General pharmacology / 002B02A03 Pharmaceutical technology. Pharmaceutical industry
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B24 Investigative techniques, diagnostic techniques (general aspects) / 002B24A Radiodiagnosis. Nmr imagery. Nmr spectrometry / 002B24A10 Miscellaneous. Technology
- Discipline
- General pharmacology Polymer industry, paints, wood Scanning and diagnostic techniques
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 21377961
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1021/bm900043e 
https://dx.doi.org/10.1021/bm900043e
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