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P-glycoprotein transporters and the gastrointestinal tract : Evaluation of the potential in vivo relevance of in vitro data employing talinolol as model compound

Author
SPAHN-LANGGUTH, H1 ; BAKTIR, G2 ; RADSCHUWEIT, A1 ; OKYAR, A2 ; TERHAAG, B3 ; ADER, P1 ; HANAFY, A1 ; LANGGUTH, P4
[1] School of Pharmacy, Martin Luther University Halle-Wittenberg, Halle/Saale, Germany
[2] Department of Pharmacology, University of Istanbul, Istanbul, Turkey
[3] Arzneimittelwerk Dresden, Radebeul, Sweden
[4] Astra Hässle AB, Mölndal, Sweden
Conference title
Clinical pharmacology of P-glycoprotein and related transporters. Part I
Conference name
Official Satellite Symposium of the 2nd Congress of the European Association of Clinical Pharmacology and Therapeutics (EACPT): Clinical pharmacology of P-glycoprotein and related transporters (EACPT): Clinical pharmacology of P-glycoprotein and related transporters (Berlin 1997)
Author (monograph)
WOODCOCK, B. G (Editor)1 ; PREISS, R (Editor)2
European Association of Clinical Pharmacology and Therapeutics, Europe (Funder/Sponsor)
[1] Institute for Clinical Pharmacology, University Hospital, Frankfurt am Main, Germany
[2] Institute of Clinical Pharmacology, University of Leipzig, Germany
Source

International journal of clinical pharmacology and therapeutics. 1998, Vol 36, Num 1, pp 16-24 ; ref : 26 ref

ISSN
0946-1965
Scientific domain
Pharmacology drugs
Publisher
Dustri, München
Publication country
Germany
Document type
Conference Paper
Language
English
Keyword (fr)
Absorption Animal Antagoniste Aralkylamine Association médicamenteuse Cellule tumorale Côlon Distribution Glycoprotéine P In vitro In vivo Interaction médicamenteuse Lignée cellulaire établie Pharmacocinétique Rat Récepteur biologique Récepteur β-adrénergique Talinolol Transporteur Tube digestif Tumeur maligne Voie intraveineuse Voie orale Vérapamil Appareil digestif pathologie Côlon pathologie Intestin pathologie Mammalia Rodentia Vertebrata
Keyword (en)
Absorption Animal Antagonist Aralkylamine Drug combination Tumor cell Colon Distribution P Glycoprotein In vitro In vivo Drug interaction Established cell line Pharmacokinetics Rat Biological receptor β-Adrenergic receptor Talinolol Conveyor Digestive tract Malignant tumor Intravenous administration Oral administration Verapamil Digestive diseases Colonic disease Intestinal disease Mammalia Rodentia Vertebrata
Keyword (es)
Absorción Animal Antagonista Aralquilamina Asociación medicamentosa Célula tumoral Colón Distribución Glycoproteina P In vitro In vivo Interacción medicamentosa Línea celular establecida Farmacocinética Rata Receptor biológico Receptor β-adrenérgico Talinolol Transportador Tubo digestivo Tumor maligno Vía intravenosa Vía oral Verapamilo Aparato digestivo patología Colón patología Intestino patología Mammalia Rodentia Vertebrata
Classification
Pascal
002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A04 Molecular and cellular biology / 002A04H Cell physiology / 002A04H06 Membrane and intracellular transports

Discipline
Molecular and cell biology
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
2145818

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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