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Polycyclic cage structures as carrier molecules for neuroprotective non-steroidal anti-inflammatory drugs

Author
PRINS, Louis H. A1 ; DU FREEZ, Jan L2 ; VAN DYK, Sandra1 ; MALAN, Sarel F1
[1] Pharmaceutical Chemistry, School of Pharmacy, North-West University, Potchefstroom 2520, South Africa
[2] Central Analytical Lahoratory. School of Pharmacy, North-West University, Potchefstroom, 2520, South Africa
Source

European journal of medicinal chemistry. 2009, Vol 44, Num 6, pp 2577-2582, 6 p ; ref : 26 ref

CODEN
EJMCA5
ISSN
0223-5234
Scientific domain
Organic chemistry; Pharmacology drugs
Publisher
Elsevier, Kidlington
Publication country
United Kingdom
Document type
Article
Language
English
Author keyword
Amantadine Antioxidant activity Blood-brain barrier permeability Non-steroidal anti-inflammatory drugs (NSAIDs) Polycyclic cage Prodrugs
Keyword (fr)
Acide acétylsalicylique Activité biologique Animal Antiinflammatoire non stéroïde Antioxydant Barrière hématoencéphalique Composé cage Composé polycyclique Distribution Dérivé de l'amantadine Encéphale Hétérocycle oxygène azote Ibuprofène In vitro In vivo Neuroprotecteur Perméabilité cellulaire Promédicament Souris Synthèse chimique Système nerveux central Tissu Voie intrapéritonéale Azaoxaheptacyclotétradécane dérivé Biodistribution Dérivé de l'acide arylpropionique Mammalia Rodentia Salicylés Vertebrata
Keyword (en)
Acetylsalicylic acid Biological activity Animal Non steroidal antiinflammatory agent Antioxidant Blood brain barrier Cage compound Polycyclic compound Distribution Amantadine derivatives Encephalon Oxygen nitrogen heterocycle Ibuprofen In vitro In vivo Neuroprotective agent Cell permeability Prodrug Mouse Chemical synthesis Central nervous system Tissue Intraperitoneal administration Arylpropionic acid derivatives Mammalia Rodentia Salicylates Vertebrata
Keyword (es)
Acetilsalicilico ácido Actividad biológica Animal Antiinflamatorio no esteroide Antioxidante Barrera hematoencefálica Compuesto jaula Compuesto policíclico Distribución Amantadina derivada Encéfalo Heterociclo oxígeno nitrógeno Ibuprofeno In vitro In vivo Neuroprotector Permeabilidad celular Promedicamento Ratón Síntesis química Sistema nervioso central Tejido Vía intraperitoneal Arilpropionico ácido derivado Mammalia Rodentia Salicilatos Vertebrata
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02N General and cellular metabolism. Vitamins

Discipline
Pharmacological treatments
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
21487750

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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