Conditional deletion of STAT5 in adult mouse hematopoietic stem cells causes loss of quiescence and permits efficient nonablative stem cell replacement
- Author
- ZHENGQI WANG1 2 ; GEQIANG LI1 2 ; TSE, William1 2 ; BUNTING, Kevin D1 2 3
[1] Department of Medicine, Hematology-Oncology, Case Western Reserve University, Cleveland, OH, United States
[2] Center for Stem Cell and Regenerative Medicine, Cleveland, OH, United States
[3] Case Comprehensive Cancer Center, Cleveland, OH, United States - Source
Blood. 2009, Vol 113, Num 20, pp 4856-4865, 10 p ; ref : 48 ref
- ISSN
- 0006-4971
- Scientific domain
- Medical oncology; Hematology
- Publisher
- Americain Society of Hematology, Washington, DC
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Animal adulte Cellule hématopoïétique Cellule souche Conditionnement atténué Délétion Facteur transcription STAT5 Hématologie Mort cellulaire Quiescence
- Keyword (en)
- Adult animal Hematopoietic cell Stem cell Non myeloablative treatment Deletion Transcription factor STAT5 Hematology Cell death Quiescence
- Keyword (es)
- Animal adulto Célula hematopoyética Célula primitiva Tratamiento no mieloablativo Deleción Factor transcripción STAT5 Hematología Muerte celular Quietud
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B19 Hematologic and hematopoietic diseases
- Discipline
- Blood diseases
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 21501372
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1182/blood-2008-09-181107 
https://dx.doi.org/10.1182/blood-2008-09-181107
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